Show simple item record

AuthorFilip, Jaroslav
AuthorPopelka, Anton
AuthorBertok, Tomas
AuthorHolazova, Alena
AuthorOsicka, Josef
AuthorKollar, Jozef
AuthorIlcikova, Marketa
AuthorTkac, Jan
AuthorKasak, Peter
Available date2021-01-27T11:06:53Z
Publication Date2017
Publication NameLangmuir
ResourceScopus
ISSN7437463
URIhttp://dx.doi.org/10.1021/acs.langmuir.7b00568
URIhttp://hdl.handle.net/10576/17472
AbstractWe describe a self-assembled monolayer (SAM) on a gold surface with a carboxybetaine ester functionality to control the interaction between DNA and gold nanoparticles via pH. The negatively charged phosphate backbone of DNA interacts with and adsorbs to the positively charged carboxybetaine esters on the SAM. DNA release can be achieved by the hydrolysis of carboxybetaine ester (CBE) to a zwitterionic carboxybetaine state. Furthermore, the adsorption of negatively charged citrate-capped gold nanoparticles to a SAM-modified plain gold surface can be controlled by the pH. The SAM based on carboxybetaine ester allows for the homogeneous adsorption of particles, whereas the SAM after hydrolysis at high pH repels AuNP adsorption. The antifouling surface properties of the surface modified with carboxybetaine were investigated with protein samples. American Chemical Society.
Languageen
PublisherAmerican Chemical Society
SubjectAntifouling
Sulfobetaine Methacrylate Polymer
Polycarboxybetaines
TitlePH-Switchable Interaction of a Carboxybetaine Ester-Based SAM with DNA and Gold Nanoparticles
TypeArticle
Pagination6657-6666
Issue Number27
Volume Number33
dc.accessType Abstract Only


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record