Open-label study of absorption and clearance of 1% voriconazole eye drops
AuthorNeoh, Chin Fen
Fullinfaw, Robert O.
Vajpayee, Rasik B.
Davies, Geoffrey E.
Kong, David C. M.
MetadataShow full item record
Twenty participants undergoing elective cataract surgery received 1% voriconazole eye drops (1 drop per eye) either 20, 40, 60, or 80 min before surgery. Median voriconazole concentrations of 1.9 to 3.2 mg/liter in aqueous humor samples were attained over the first 80 min, which were higher than in vitro MIC90 values for typical fungi that cause keratitis.
- Pharmacy Research [686 items ]