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Population immunity of natural infection, primary-series vaccination, and booster vaccination in Qatar during the COVID-19 pandemic: an observational study

Suelen H., Qassim; Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; ... more authors ... less authors ( Elsevier , 2023 , Article)

BackgroundWaning of natural infection protection and vaccine protection highlight the need to evaluate changes in population immunity over time. Population immunity of previous SARS-CoV-2 infection or of COVID-19 vaccination ...

BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents

Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ... less authors ( Elsevier , 2023 , Other)

COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ...

Long-term COVID-19 booster effectiveness by infection history and clinical vulnerability and immune imprinting: a retrospective population-based cohort study

Hiam, Chemaitelly; Ayoub, Houssein H; Tang, Patrick; Coyle, Peter; Yassine, Hadi M; ... more authors ... less authors ( Elsevier , 2023 , Article)

BackgroundLong-term effectiveness of COVID-19 mRNA boosters in populations with different previous infection histories and clinical vulnerability profiles is inadequately understood. We aimed to investigate the effectiveness ...

Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar

Chemaitelly, Hiam; Ayoub, Houssein H; Faust, Jeremy Samuel; Coyle, Peter; Tang, Patrick; ... more authors ... less authors ( BMJ Publishing Group , 2023 , Article)

Objective To assess the evolution of COVID-19 severity and fatality in a unique setting that consistently applied, throughout the pandemic, rigorous and standardised criteria for defining severe COVID-19 outcomes. Methods ...

History of primary-series and booster vaccination and protection against Omicron reinfection

Chemaitelly, Hiam; Ayoub, Houssein H.; Tang, Patrick; Coyle, Peter V.; Yassine, Hadi M.; ... more authors ... less authors ( American Association for the Advancement of Science , 2023 , Article)

Laboratory evidence suggests a possibility of immune imprinting for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We investigated the differences in the incidence of SARS-CoV-2 reinfection in a ...

Effectiveness of two and three doses of COVID-19 mRNA vaccines against infection, symptoms, and severity in the pre-omicron era: A time-dependent gradient

Layan, Sukik; Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; ... more authors ... less authors ( Elsevier , 2024 , Article)

BackgroundVaccines were developed and deployed to combat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to characterize patterns in the protection provided by the BNT162b2 and ...

Prevalence of hepatitis B and C viruses among migrant workers in Qatar.

Nasrallah, Gheyath K; Chemaitelly, Hiam; Ismail, Ahmed I A; Nizamuddin, Parveen B; Al-Sadeq, Duaa W; ... more authors ... less authors ( Springer Nature , 2024 , Article)

Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft ...

Estimating protection afforded by prior infection in preventing reinfection: Applying the test-negative study design.

Ayoub, Houssein H; Tomy, Milan; Chemaitelly, Hiam; Altarawneh, Heba N; Coyle, Peter; ... more authors ... less authors ( Oxford University Press , 2023 , Article)

The COVID-19 pandemic has highlighted the need to use infection testing databases to rapidly estimate effectiveness of prior infection in preventing reinfection ($P{E}_S$) by novel SARS-CoV-2 variants. Mathematical modeling ...

Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar's experience

Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R.; ... more authors ... less authors ( Edinburgh University Global Health Society , 2022 , Article)

Background The effective reproduction number, Rt, is a tool to track and understand pandemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset of ...

BNT162b2 Versus mRNA-1273 Vaccines: Comparative Analysis of Long-Term Protection Against SARS-CoV-2 Infection and Severe COVID-19 in Qatar

Chemaitelly, Hiam; Ayoub, Houssein H; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; ... more authors ... less authors ( Wiley , 2024 , Article)

Background: This study provides a head-to-head comparison of the protection provided by the BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2 infection and against severe COVID-19, covering primary series and third ...