Effects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 omicron infections.
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Date
2022-05-27Author
Qassim, Suelen HChemaitelly, Hiam
Ayoub, Houssein H
AlMukdad, Sawsan
Tang, Patrick
Hasan, Mohammad R
Yassine, Hadi M
Al-Khatib, Hebah A
Smatti, Maria K
Abdul-Rahim, Hanan F
Nasrallah, Gheyath K
Al-Kuwari, Mohamed Ghaith
Al-Khal, Abdullatif
Coyle, Peter
Kaleeckal, Anvar Hassan
Shaik, Riyazuddin Mohammad
Latif, Ali Nizar
Al-Kuwari, Einas
Jeremijenko, Andrew
Butt, Adeel A
Bertollini, Roberto
Al-Romaihi, Hamad Eid
Al-Thani, Mohamed H
Abu-Raddad, Laith J
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Compared to BA.1, BA.2 was associated with lower RT-qPCR cycle threshold (Ct) value-3.53 fewer cycles (95% CI: 3.46-3.60), signifying higher infectiousness. This may reflect higher viral load and/or longer duration of infection for BA.2. Natural immunity from previous infection and booster vaccination were associated with less infectious breakthrough infections.
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