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Now showing items 14063-14082 of 26404
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Molecular dynamics of CH4/CO2 on calcite for enhancing gas recovery
( John Wiley and Sons Inc , 2022 , Article)The effect of temperature and pressure on the adsorption of CO2 and CH4 gases on calcite (104) has been studied by means of classical molecular dynamics. The results show that carbon dioxide greatly improves methane ... -
Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe's disease.
( Taylor & Francis , 2020 , Article)Krabbe disease (KD), also known as globoid cell leukodystrophy disease, is an autosomal recessive lysosomal storage genetic disorder, which is caused by the deficiecncy of galactocerebrosidase (GALC) coding gene (). This ... -
Molecular dynamics, residue network analysis, and cross-correlation matrix to characterize the deleterious missense mutations in GALE causing galactosemia III.
( Springer , 2021 , Article)Epimerase-deficiency galactosemia (EDG) is caused by mutations in the UDP-galactose 4'-epimerase enzyme, encoded by gene GALE. Catalyzing the last reaction in the Leloir pathway, UDP-galactose-4-epimerase catalyzes the ... -
Molecular dynamics-based analyses of the structural instability and secondary structure of the fibrinogen gamma chain protein with the D356V mutation.
( Taylor & Francis , 2016 , Article)Mutations in the fibrinogen gamma chain (FGG) gene have been associated with various disorders, such as dysfibrinogenemia, thrombophilia, and hypofibrinogenemia. A literature survey showed that a residue exchange in ... -
Molecular epidemiology and genotype distribution of Human Papillomavirus (HPV) among Arab women in the state of Qatar
( BioMed Central Ltd. , 2014 , Article)Background: Human Papilloma Virus (HPV) infection is the major cause of cervical cancer worldwide. With limited data available on HPV prevalence in the Arab countries, this study aimed to identify the prevalence and ... -
Molecular Epidemiology and Genotype Distribution of Human Papillomavirus Among Arab Women in State of Qatar
(2014 , Master Thesis)Background: Human papillomavirus (HPV) are the most commonly known sexually transmitted agents. To date, few reports are available on distribution of most prevalent and variants types of HPV in Arab women. Therefore, the ... -
Molecular epidemiology of influenza, RSV, and other respiratory infections among children in Qatar: A six years report (2012–2017)
( Elsevier B.V. , 2020 , Article)Background: Studies on the etiology of respiratory infections among children in Qatar and surrounding countries are limited. Objectives: To describe the prevalence and seasonality of RSV, influenza, and other respiratory ... -
Molecular epidemiology of Rotavirus in children with gastroenteritis in Qatar
( OMICS , 2019 , Conference Paper)Acute gastroenteritis remains a major cause of morbidity and mortality of young children worldwide. The vast majority of diarrhea cases in developing and developed countries are attributable to the viruses and to a lesser ... -
Molecular epidemiology, genetic diversity, and vaccine availability of viral acute gastroenteritis in the middle East and North Africa (MENA) region
( Elsevier , 2022 , Article)Acute gastroenteritis is the cause of considerable mortality and morbidity worldwide, particularly among children under five years in underdeveloped countries. Most acute gastroenteritis (AGE) cases are attributed to viral ... -
Molecular Evidence of Anticancer Activity of Camel Milk Combined with Camel Urine
( Austin Publishing Group , 2021 , Article)Camel Milk (CM) and Camel Urine (CU) is a traditional practice in the Middle East and other countries as an alternative treatment against cancer. We hypothesized that a combination of CM and CU (CM+CU), used at ... -
Molecular Evidence of Breast Cancer Cell Proliferation Inhibition by a Combination of Selected Qatari Medicinal Plants Crude Extracts
( MDPI , 2023 , Article): Breast cancer (BC) is the most common malignancy, and conventional medicine has failed to establish efficient treatment modalities. Conventional medicine failed due to lack of knowledge of the mechanisms that underpin ... -
MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS
(2021 , Master Thesis)Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. Chemoresistance is attributed to the presence of long-lived cancer stem cells (CSCs) responsible for therapy failure. This study ... -
Molecular identification and biocontrol of ochratoxigenic fungi and ochratoxin A in animal feed marketed in the state of Qatar
( Elsevier Ltd , 2023 , Article)Ochratoxin A (OTA) is a toxic fungal metabolite produced by some Aspergillus and Penicillium species. This work was designed to explore the presence of OTA and ochratoxigenic fungi in feed grains marketed in Qatar and their ... -
Molecular identification and characterization of Cryptosporidium spp. among pediatric and food-handlers subjects in Qatar
( Frontiers Media , 2017 , Article)World Health Organization (WHO) has identified Cryptosporidium spp. as globally the most common diarrhea-causing protozoan. Its transmission occurs mainly through ingestion of water or food contaminated with the feces of ... -
Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling
( Frontiers Media S.A. , 2020 , Article)In December 2019, reports of viral pneumonia came out of Wuhan city in Hubei province in China. In early 2020, the causative agent was identified as a novel coronavirus (CoV) sharing some sequence similarity with SARS-CoV ... -
Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach.
( Elsevier , 2019 , Article)The G2019S substitution in the Leucine-rich repeat kinase 2 (LRRK2) is significantly associated with Parkinson's disease (PD). This substitution was identified in both familial and sporadic forms of PD with a higher ... -
Molecular investigation of waterborne protozoan contamination using marine Demospongiae
( Elsevier , 2024 , Article)Sponges play important role within aquatic ecosystems due to their diverse abilities including filter-based feeding mechanisms. Hence, this study evaluated the potential use of sponges as ecological biomonitors for water ... -
MOLECULAR LEVEL UNDERSTANDING OF NANOCLAY DISPERSION IN POLYSULFONE, POLYIMIDE, AND THEIR BLEND COMPOSITES
(2016 , Master Thesis)Polymer composites based on polysulfone (PSF) and polyimide (PI) are used as membranes for gas separation and water purification applications. However, structure composition related issues limit the performance of the used ... -
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
( hindawi , 2020 , Article)Hypertension induces vascular hypertrophy, which changes blood vessels structurally and functionally, leading to reduced tissue perfusion and further hypertension. It is also associated with dysregulated levels of the ... -
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
( MDPI , 2020 , Article Review)Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ...