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Claudin-1, A Double-Edged Sword in Cancer.
(
MDPI
, 2020 , Article Review)
Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ...
Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications
(
MDPI
, 2020 , Article Review)
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, ...
GATA-3 as a potential therapeutic target for insulin resistance and type 2 diabetes mellitus.
(
PubMed Central
, 2020 , Article Review)
Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes as it leads to ectopic fat deposition. The anti-adipogenic transcription factor GATA-3 was ...
Advances in Cardiovascular Biomarker Discovery.
(
MDPI
, 2020 , Article Review)
Cardiovascular diseases are the leading causes of mortality worldwide. Among them, hypertension and its pathological complications pose a major risk for the development of other cardiovascular diseases, including heart ...
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
(
MDPI
, 2020 , Article Review)
Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ...
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
(
Elsevier
, 2020 , Article Review)
ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ...
Balancing the benefits from the water–energy–land–food nexus through agroforestry in the Sahel
(
Elsevier
, 2020 , Article Review)
Regions affected by resource scarcity, poverty, and land-use conflicts need to advocate the merits of practices strongly grounded in sustainable land management. This review paper provides an analysis of agroforestry as ...
Consanguineous marriage in the Arab societies
(
MedCrave
, 2020 , Article Review)
Endogamous and consanguineous marriage is estimated to comprise 20% of all marriages in the contemporary world. In Arabia, however, it is estimated to characterize approximately half of all marriages. Overall, this is ...
SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities.
(
MDPI
, 2020 , Article Review)
Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to ...
Growing Burden of Hypertension in China: Causes, Challenges, and Opportunities
(
Chinese Center for Disease Control and Prevention (China CDC)
, 2020 , Article Review)
Cardiovascular disease (CVD) is the leading cause of
death in China, and an estimated 290 million
individuals are affected by CVD in China (1).
Hypertension is the most important risk factor of
CVD (2). Good control ...