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Now showing items 11-20 of 26
Imatinib‑ and ponatinib‑mediated cardiotoxicity in zebrafish embryos and H9c2 cardiomyoblasts
(
Spandidos Publications
, 2024 , Article)
Tyrosine kinase inhibitors (TKIs) offer targeted therapy for cancers but can cause severe cardiotoxicities. Determining their dose‑dependent impact on cardiac function is required to optimize therapy and minimize adverse ...
Hemodynamic Studies for Analyzing the Teratogenic Effects of Drugs in the Zebrafish Embryo.
(
Humana Press
, 2018 , Book chapter)
Investigations of teratogenic effects of drugs generally involve testing the drug on animals and zebrafish embryo is a commonly used animal model for that purpose. In these studies, cardiovascular function of the animals ...
Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model.
(
MDPI
, 2019 , Article)
Advanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen ...
The First International Zebrafish Conference/Workshop in Qatar.
(
Mary Ann Liebert
, 2019 , Article)
A zebrafish conference/workshop was held in Qatar between April 13 and 17, 2019. The aim of the event was to promote zebrafish research in Qatar and in Middle East/Asia by bringing together local zebrafish researchers with ...
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
(
MDPI
, 2019 , Article)
The use of chitosan nanoparticles (ChNPs) in various biological and environmental
applications is attracting great interest. However, potential side effects related to ChNP toxicity
remain the major limitation hampering ...
Generating an imagingbased approach for enhanced structural and functional analysis of zebrafish cardiovascular systems
(
HBKU Press
, 2018 , Conference)
Cardiovascular diseases (CVDs) have latterly become one of the leading cause of death and impairment
worldwide. According to the World Health Organization (WHO), data estimation in 2008 were about
17.3, 7.3 and 6.2 million ...
Zebrafish larvae as a model to demonstrate secondary iron overload.
(
Wiley
, 2018 , Article)
Thalassemia is the most common genetically inherited blood disorder arising from a defect in hemoglobin production, resulting in ineffective erythropoiesis and severe hemolytic anemia. While transfusion therapy corrects ...
Iron shuttle chelation therapy enhances to reduce misplaced iron on secondary iron overloaded adult zebrafish
(2017 , Conference)
Thalassemia is the most common genetically inherited blood disorder in the world arises from defect in hemoglobin
production, results in ineffective erythropoiesis and the rapid destruction of RBC in the periphery that ...
Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish.
(
Frontiers Media
, 2019 , Article)
Ultrasonography is the most widely used imaging technique in cardiovascular medicine. In this technique, a piezoelectric crystal produces, sends, and receives high frequency ultrasound waves to the body to create an image ...
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
(
John Wiley & Sons
, 2024 , Article)
Calmodulin (CaM) is a ubiquitous, small cytosolic calcium (Ca2+)-binding sensor that plays a vital role in many cellular processes by binding and regulating the activity of over 300 protein targets. In cardiac muscle, CaM ...