عرض بسيط للتسجيلة

المؤلفZupin, L.
المؤلفZupin, Luisa
المؤلفGratton, Rossella
المؤلفFontana, Francesco
المؤلفClemente, Libera
المؤلفPascolo, Lorella
المؤلفRuscio, Maurizio
المؤلفCrovella, Sergio
تاريخ الإتاحة2022-01-24T05:24:41Z
تاريخ النشر2021-04-01
اسم المنشورJournal of Biophotonics
المعرّفhttp://dx.doi.org/10.1002/jbio.202000496
الاقتباسZupin, L, Gratton, R, Fontana, F, et al. Blue photobiomodulation LED therapy impacts SARS-CoV-2 by limiting its replication in Vero cells. J. Biophotonics. 2021; 14:e202000496. https://doi.org/10.1002/jbio.202000496
الرقم المعياري الدولي للكتاب1864063X
معرّف المصادر الموحدhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85101809002&origin=inward
معرّف المصادر الموحدhttp://hdl.handle.net/10576/25805
الملخصThe study of any intervention able to counteract SARS-CoV-2 pandemic is considerably envisaged. It was previously shown, in in vitro models of infections, that the LED blue light is able to decrease the viral load of HSV-1 and ZIKV. In our study, LED photobiomodulation therapy (PBMT) at blue wavelengths (450, 454 and 470 nm) was tested in an in vitro model of SARS-CoV-2 infection, employing three experimental settings: SARS-CoV-2 was irradiated and then transferred to cells; already infected cells were irradiated; cells were irradiated prior to infection. A decrement of the viral load was observed when previously infected cells were irradiated with all three tested wavelengths and relevant effects were registered especially at 48 hours post-infection, possibly suggesting that the blue light could interfere with the intracellular viral replication machinery. Our in vitro findings could represent the starting point for translational applications of PBMT as a supportive approach to fight SARS-CoV-2.
اللغةen
الناشرWiley
الموضوعblue LED
photobiomodulation therapy
SARS-CoV-2
Vero E6 cell line
العنوانBlue photobiomodulation LED therapy impacts SARS-CoV-2 by limiting its replication in Vero cells
النوعOther
رقم العدد4
رقم المجلد14
ESSN1864-0648
dc.accessType Full Text


الملفات في هذه التسجيلة

Thumbnail

هذه التسجيلة تظهر في المجموعات التالية

عرض بسيط للتسجيلة