Browsing Medicine Research by Author "Cecchi, Marta"
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Dexamethasone induces the expression and function of tryptophan-2-3-dioxygenase in sk-mel-28 melanoma cells
Cecchi, Marta; Paccosi, Sara; Silvano, Angela; Eid, Ali Hussein; Parenti, Astrid ( MDPI , 2021 , Article)Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation, clinical trials showed that inhibitors of the ubiquitously expressed ...