Browsing Medicine Research by Author "Dallaire, Paul"
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Comprehensive Signaling Profiles Reveal Unsuspected Functional Selectivity of δ-Opioid Receptor Agonists and Allow the Identification of Ligands with the Greatest Potential for Inducing Cyclase Superactivation
Mansour, Ahmed; Nagi, Karim; Dallaire, Paul; Lukasheva, Viktoriya; Le Gouill, Christian; Bouvier, Michel; Pineyro, Graciela... more authors ... less authors ( American Chemical Society , 2021 , Article)Prolonged exposure to opioid receptor agonists triggers adaptations in the adenylyl cyclase (AC) pathway that lead to enhanced production of cyclic adenosine monophosphate (cAMP) upon withdrawal. This cellular phenomenon ...