Browsing Medicine Research by Author "Sahebkar, Amirhossein"

Now showing items 21-24 of 24

    • The pharmaco-epigenetics of hypertension: a focus on microRNA 

      Yaacoub, Serge; Boudaka, Ammar; AlKhatib, Ali; Pintus, Gianfranco; Sahebkar, Amirhossein; ... more authors ( Springer Nature , 2024 , Article)
      Hypertension is a major harbinger of cardiovascular morbidity and mortality. It predisposes to higher rates of myocardial infarction, chronic kidney failure, stroke, and heart failure than most other risk factors. By 2025, ...

    • Pleiotropic properties of statins via angiogenesis modulation in cardiovascular disease 

      Fatemeh, Zahedipour; Butler, Alexandra E.; Eid, Ali H.; Sahebkar, Amirhossein ( Elsevier , 2022 , Article)
      Inhibition of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase by statins is affected by inhibiting the active site of the enzyme in a competitive manner. Statins reduce plasma cholesterol by inhibiting its de novo ...

    • Selective Activation of G protein-coupled Estrogen Receptor 1 Attenuates Atherosclerosis. 

      Eid, Ali; Sahebkar, Amirhossein; Haider, M Zulqarnein ( Bentham Science Publishers , 2023 , Article Review)
      Atherosclerosis remains a leading contributor to cardiovascular disease-associated morbidity and mortality. Interestingly, the death rate is higher in men than women from atherosclerosis, and the risk increases for ...

    • Therapeutic effects of statins on osteoarthritis: A review 

      Saberianpour, Shirin; Abolbashari, Samaneh; Modaghegh, Mohamad H.S.; Karimian, Maryam S.; Eid, Ali H.; ... more authors ( Wiley , 2022 , Article Review)
      Osteoarthritis (OA) is a progressive joint disease. The etiology of OA is considered to be multifactorial. Currently, there is no definitive treatment for OA, and the existing treatments are not very effective. ...