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السجلات المعروضة 41 -- 60 من 1378
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Male infertility-linked point mutation reveals a vital binding role for the C2 domain of sperm PLC?
( Portland Press Ltd , 2017 , Article)Sperm-specific phospholipase C zeta (PLC?) is widely considered to be the physiological stimulus that evokes intracellular calcium (Ca2+) oscillations that are essential for the initiation of egg activation during mammalian ... -
Role of Qat chewing and mate consumption in human oral carcinogenesis
( Springer International Publishing , 2017 , Book chapter)[No abstract available] -
Nonphysician Out-of-Hospital Rapid Sequence Intubation Success and Adverse Events: A Systematic Review and Meta-Analysis
( Elsevier , 2017 , Article)Study objective: Rapid sequence intubation performed by nonphysicians such as paramedics or nurses has become increasingly common in many countries; however, concerns have been stated in regard to the safe use and ... -
The role and mechanism of action of sperm PLC-zeta in mammalian fertilisation
( Portland Press Ltd , 2017 , Article Review)At mammalian fertilisation, the fundamental stimulus that triggers oocyte (egg) activation and initiation of early embryonic development is an acute rise of the intracellular-free calcium (Ca2+) concentration inside the ... -
Country and gender-specific achievement of healthy nutrition and physical activity guidelines: Latent class analysis of 6266 university students in Egypt, Libya, and Palestine
( MDPI AG , 2017 , Article)Research on healthy behaviour such as physical activity and healthy nutrition and their combination is lacking among university students in Arab countries. The current survey assessed healthy nutrition, and moderate/vigorous ... -
Thujone inhibits the function of 7-nicotinic acetylcholine receptors and impairs nicotine-induced memory enhancement in one-trial passive avoidance paradigm
( Elsevier Ireland Ltd , 2017 , Article)Effects of thujone, a major ingredient of absinthe, wormwood oil and some herbal medicines, were tested on the function of 7 subunit of the human nicotinic acetylcholine (7 nACh) receptor expressed in Xenopus oocytes using ... -
Drug release kinetics from a drug-eluting stent with asymmetrical coat
( IMR Press Limited , 2017 , Article)The aim of this study was to investigate the drug release profiles of biodegradable polymer sirolimus- or paclitaxel-eluting stents with asymmetrical coating (BPSES-A or BPPES-A) both in vitro and in vivo. In vitro, the ... -
Continuity of sleep problems from adolescence to young adulthood: results from a longitudinal study
( Elsevier Inc , 2017 , Article)Background Considering the lack of evidence on incidence and continuity of sleep problems from adolescence to young adulthood, this study explores sleep problems’ incidence and their continuation rates from 14 to 21 ... -
Development of oral cancer: Risk factors and prevention strategies
( Springer International Publishing , 2017 , Book)This book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. ... -
Synergistic antipruritic effects of gamma aminobutyric acid A and B agonists in a mouse model of atopic dermatitis
( Mosby Inc. , 2017 , Article)Background Despite recent insights into the pathophysiology of acute and chronic itch, chronic itch remains an often intractable condition. Among major contributors to chronic itch is dysfunction of spinal cord gamma ... -
High-risk human papillomaviruses and epstein-barr virus presence and crosstalk in human oral carcinogenesis
( Springer International Publishing , 2017 , Book chapter)Oral cancer is the most frequent type of malignancy of the head and neck area worldwide. This cancer is a major cause of mortality in several parts of the world especially in certain Asian countries. In fact, the majority ... -
Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
( Elsevier B.V. , 2017 , Article)The critical role of α1-glycine receptor (α1-GLYRs) in pathological conditions such as epilepsy is well known. In the present study, structure-activity relations for a series of phenylalanine derivatives carrying selected ... -
The expansion of soil-transmitted helminth control strategies ? Authors' reply
( Lancet Publishing Group , 2017 , Article)[No abstract available] -
In honour of Professor Ruth Duncan, recipient of the Journal of Drug Targeting's Lifetime Achievement Award for 2017
( Taylor and Francis Ltd , 2017 , Other)[No abstract available] -
Prevention of oral cancer
( Springer International Publishing , 2017 , Book chapter)Oral cancer has become a major debilitating incidence in both genders alike. Oral cancer, a part of head and neck cancer, is a combination of two types of cancer: oral cavity cancer and oropharyngeal cancer. The most common ... -
Medical students' perceptions of supporting pharmacology learning in english by key information prepared in arabic
( World Health Organization , 2017 , Article)We explored medical students' perceptions of supporting pharmacology self-learning in English by focused materials prepared in Arabic. This study targeted third-year medical students at the Arabian Gulf University in Bahrain ... -
Acute exposure to cigarette smoking followed by myocardial infarction aggravates renal damage in an in vivo mouse model
( Hindawi Limited , 2017 , Article)Cigarette smoking (S) is a risk factor for progressive chronic kidney disease, renal dysfunction, and renal failure. In this study, the effect of smoking on kidney function was investigated in a mouse model of myocardial ... -
Frequency of adjustment with comorbidity and illness severity scores and indices in cardiac arrest research
( Elsevier , 2017 , Article)Background Previous research demonstrates that results from observational research correlate well with results from clinical trials, and if the former are well designed these can guide clinical practice. Observational ... -
Total temporomandibular joint replacement prostheses: a systematic review and bias-adjusted meta-analysis
( Elsevier , 2017 , Article)The aim of the present study was to determine which prosthesis has resulted in the best outcomes after total temporomandibular joint replacement (TMJR). A comprehensive electronic search was undertaken in September 2015. ... -
Effect of Immediate Administration of Antibiotics in Patients With Sepsis in Tertiary Care: A Systematic Review and Meta-analysis
( Elsevier , 2017 , Article)Purpose The goal of this review was to synthesize existing evidence regarding outcomes (mortality) for patients who present to the emergency department, are administered antibiotics immediately (within 1 hour) or later (>1 ...