Browsing Medicine Research by Publication Date
Now showing items 121-140 of 1357
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Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
( Elsevier , 2018 , Article)Calmodulin (CaM) is a cytoplasmic multifunctional calcium (Ca2+)-binding messenger that interacts with the cardiac ryanodine receptor (RyR2), a large transmembrane Ca2+ channel that mediates Ca2+ release from the sarcoplasmic ... -
The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2018 , Article)The Hedgehog (Hh) signaling pathway was first identified in the common fruit fly. It is a highly conserved evolutionary pathway of signal transmission from the cell membrane to the nucleus. The Hh signaling pathway plays ... -
Assessing the use of the anatomical method for the estimation of sub-adult stature in Black South Africans
( Elsevier , 2018 , Article)Stature estimation is rarely attempted in sub-adults due to the general lack of available standards as a result of the dearth of sufficiently large sub-adult skeletal collections with known demographic information. To ... -
Long Sun-Exposures Influencing High Sub-Cutaneous Synthesis of Vitamin-D3 may be Associated with Exacerbation of Symptoms in Allergic-Asthma.
(2018 , Article)Does excessive sun-exposure, non-use of sunscreen and/or high doses of vitamin-D3 supplements provoke exacerbation of asthma? Clinical examinations, retrospective records-access and questionnaire surveys were distributed ... -
Comparative effectiveness of malaria prevention measures: a systematic review and network meta-analysis.
( BMC , 2018 , Article Review)Malaria causes significant morbidity and mortality worldwide. There are several preventive measures that are currently employed, including insecticide-treated nets (ITNs, including long-lasting insecticidal nets and ... -
Sleep problems in adolescence and overweight/obesity in young adults: is there a causal link?
( Elsevier , 2018 , Article)This study aims to explore if there is a causal association between adolescence sleep problems and overweight/obesity (Ow/Ob) in young adults. Youth self-reports were used to explore if adolescence (mean age 13.90 years, ... -
Antenatal diagnosis of fetal skeletal malformation
( Jaypee Brothers Medical Publishers , 2018 , Article)Skeletal dysplasia encompasses a heterogamous group of disorders. In this disorder, there are abnormalities involving primarily the fetal skeleton and it may involve other fetal organs. These changes can be lethal or ... -
Composition of the immune microenvironment differs between carcinomas metastatic to the lungs and primary lung carcinomas.
( Elsevier , 2018 , Article)Lungs are among the most common sites for development of both primary and metastatic carcinomas. Tumor cells expression (TC) of PD-L1 is an important predictor of the of response to immune check-point inhibition in NSCLC, ... -
Proteomic Profiling of Diffuse Large B-Cell Lymphomas
( Karger Publishers , 2018 , Article)The aim of this study was to identify differences in proteome profiles of diffuse large B-cell lymphoma (DLBCL) of nongerminal center (non-GC) versus GC type in the search for new markers and drug targets. Six DLBCL, with ... -
The Role of Epstein-Barr Virus in Cervical Cancer: A Brief Update.
( Frontiers Media , 2018 , Article Review)Epstein-Barr virus (EBV) belongs to the group of gamma-herpes viruses and was the first recognized human oncovirus. EBV is responsible for infectious mononucleosis and multiple lymphoid and epithelial malignancies including ... -
Epstein-Barr Virus in Gliomas: Cause, Association, or Artifact?
( Frontiers Media , 2018 , Article Review)Gliomas are the most common malignant brain tumors and account for around 60% of all primary central nervous system cancers. Glioblastoma multiforme (GBM) is a grade IV glioma associated with a poor outcome despite recent ... -
Effect of cell-phone radiofrequency on angiogenesis and cell invasion in human head and neck cancer cells.
( Wiley , 2018 , Article)Today, the cell phone is the most widespread technology globally. However, the outcome of cell-phone radiofrequency on head and neck cancer progression has not yet been explored. The chorioallantoic membrane (CAM) and human ... -
Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression.
( Frontiers Media , 2018 , Article Review)Oncoviruses are implicated in around 20% of all human cancers including both solid and non-solid malignancies. Epstein-Barr virus (EBV) and human papillomaviruses (HPVs) are the most common oncoviruses worldwide. Currently, ... -
Measurements of the talus in the assessment of population affinity
( Elsevier Ltd , 2018 , Article)© 2018 Elsevier B.V. As part of their routine work, forensic anthropologists are expected to report population affinity as part of the biological profile of an individual. The skull is the most widely used bone for the ... -
Dimensions around the nutrient foramina of the tibia and fibula in the estimation of sex
( Elsevier Ltd , 2018 , Article)© 2018 Elsevier B.V. Sex estimation from skeletal remains is one of the key components in establishing a biological profile and consequent identification of an individual in a forensic and medico-legal practice. The use ... -
Intersection between genes controlling vascularization and angiogenesis in renal cell carcinomas
( Springer Nature , 2018 , Article)To show that application of the systemic analysis may significantly improve comparison of different datasets. Different genes and proteins may converge on the same functional outputs. A comparison of 2 datasets by only ... -
Health Outcomes from Multidrug-Resistant Salmonella Infections in High-Income Countries: A Systematic Review and Meta-Analysis
( Mary Ann Liebert , 2018 , Article)Copyright © 2018, Mary Ann Liebert, Inc. Background: Salmonella is a leading cause of foodborne enterocolitis worldwide. Antimicrobial use in food animals is the driving force for antimicrobial resistance among Salmonella ... -
Towards Molecular Profiling in Multiple Myeloma: A Literature Review and Early Indications of Its Efficacy for Informing Treatment Strategies.
( MDPI , 2018 , Article)Multiple myeloma (MM), the second most common hematologic malignancy, is characterized by the clonal expansion of plasma cells. Despite dramatic improvements in patients' survival over the past decade due to advances in ... -
Co-Incidence of Epstein-Barr Virus and High-Risk Human Papillomaviruses in Cervical Cancer of Syrian Women.
( Frontiers Media , 2018 , Article)Epstein-Barr virus (EBV) has been recently shown to be co-present with high-risk human papillomaviruses (HPVs) in human cervical cancer; thus, these oncoviruses play an important role in the initiation and/or progression ... -
Inositol 1,4,5-Trisphosphate Receptors in Hypertension.
( Frontiers Media , 2018 , Article Review)Chronic hypertension remains a major cause of global mortality and morbidity. It is a complex disease that is the clinical manifestation of multiple genetic, environmental, nutritional, hormonal, and aging-related disorders. ...