Browsing Medicine Research by Publisher "BioMed Central"

Now showing items 1-4 of 4

    • Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) 

      Sartelli, Massimo; Weber, Dieter; Ruppé, Etienne; Bassetti, Matteo; Wright, Brian; ... more authors ( BioMed Central , 2016 , Article)
      Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients. The cornerstones in the management of complicated IAIs are timely ...

    • Comparative efficacy and safety of PD-1/PD-L1 inhibitors in triple negative breast cancer: a systematic review and network meta-analysis of randomized controlled trials. 

      Elmakaty, Ibrahim; Abdo, Ruba; Elsabagh, Ahmed; Elsayed, Abdelrahman; Malki, Mohammed Imad ( BioMed Central , 2023 , Article)
      Triple-Negative Breast Cancer (TNBC) is a lethal subtype of breast cancer with limited treatment options. The purpose of this Network Meta-Analysis (NMA) is to compare the efficacy and safety of inhibitors of programmed ...

    • Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis 

      Kanoni, Stavroula; Graham, Sarah E.; Wang, Yuxuan; Surakka, Ida; Ramdas, Shweta; ... more authors ( BioMed Central , 2022 , Article)
      Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding ...

    • Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease 

      Majbour, Nour K.; Vaikath, Nishant N.; van Dijk, Karin D.; Ardah, Mustafa T.; Varghese, Shiji; ... more authors ( BioMed Central , 2016 , Article)
      Background Despite decades of intensive research, to date, there is no accepted diagnosis for Parkinson’s disease (PD) based on biochemical analysis of blood or CSF. However, neurodegeneration in the brains of PD patients ...