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Contribution of Glycosaminoglycan binding in CCL21-mediated Migration of Breast Cancer cells
(
Qatar University Press
, 2021 , Poster)
Lymph node metastasis constitutes a key event in Breast Cancer progression and it is a process at least partially mediated by the chemokine CCR7. Chemokine function is dependent upon their binding to both cell-surface ...
Prevalence of Asymptomatic Hyperuricemia and its Association with Prediabetes, Dyslipidemia and Subclinical Inflammation Markers among Young Healthy Adults in Qatar
(
Qatar University Press
, 2021 , Poster)
Aim: To investigate the prevalence of asymptomatic hyperuricemia in Qatar and to examine its association with changes in markers of dyslipidemia, prediabetes and subclinical inflammation. Methods: A cross-sectional study ...
Pyocyanin pigment from Pseudomonas aeruginosa modulates innate immune defenses in macrophages
(
Qatar University Press
, 2021 , Poster)
Background: Pseudomonas aeruginosa is a well-known opportunistic pathogen. The gram-negative bacillus, commonly associated with hospital-acquired infections, utilizes the host's impaired immune responses to establish ...
Characterising Alzheimer's disease through integrative NMR- and LC-MS-based metabolomics
(
Elsevier
, 2021 , Article)
BackgroundAlzheimer's Disease (AD) is a complex and multifactorial disease and novel approaches are needed to illuminate the underlying pathology. Metabolites comprise the end-product of genes, transcripts, and protein ...
Follicular dendritic cells
(
Wiley
, 2021 , Article Review)
Follicular dendritic cells (FDCs) are unique accessory immune cells that contribute to the regulation of humoral immunity. They are multitasker cells essential for the organization and maintenance of the lymphoid architecture, ...
Comprehensive Signaling Profiles Reveal Unsuspected Functional Selectivity of δ-Opioid Receptor Agonists and Allow the Identification of Ligands with the Greatest Potential for Inducing Cyclase Superactivation
(
American Chemical Society
, 2021 , Article)
Prolonged exposure to opioid receptor agonists triggers adaptations in the adenylyl cyclase (AC) pathway that lead to enhanced production of cyclic adenosine monophosphate (cAMP) upon withdrawal. This cellular phenomenon ...
Molecular Evidence of Anticancer Activity of Camel Milk Combined with Camel Urine
(
Austin Publishing Group
, 2021 , Article)
Camel Milk (CM) and Camel Urine (CU) is a traditional practice in the
Middle East and other countries as an alternative treatment against cancer. We
hypothesized that a combination of CM and CU (CM+CU), used at ...
Mania and hypomania associated with COVID-19: a series of 15 cases seen by the consultation-liaison psychiatry service in Qatar
(
Hamad bin Khalifa University Press (HBKU Press)
, 2021 , Article)
Background: A range of neuropsychiatric diagnoses have been reported in association with coronavirus disease 2019 (COVID-19). However, only sporadic cases of mania or hypomania have been reported in patients with COVID-19. ...
Cardiovascular risk assessment for patients with serious mental illnesses: An internal review
(
Hamad bin Khalifa University Press (HBKU Press)
, 2021 , Article)
Cardiovascular diseases (CVD) are the leading cause of excess premature mortality among patients with serious mental illness (SMI), mainly because of higher cardiovascular risk and metabolic syndrome compared to the general ...
Development of an in-house COVID-19 serology ELISA Test
(
Hamad bin Khalifa University Press (HBKU Press)
, 2021 , Article)
Background: COVID-19 pandemic created an unprecedented demand for reagents and diagnostic tools to confirm COVID-19 cases. Thus, the development of a robust in-house diagnostic test is considered of high importance. Within ...