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Now showing items 21-30 of 272
A large, highly vascularized sacrococcygeal teratoma in a preterm male infant: A case report.
(
Elsevier
, 2021 , Article)
Sacrococcygeal teratoma (SCT) is a rare tumor with an incidence of 1:35.000/40.000 live births. SCTs are composed of both cystic and solid components. Predominantly cystic SCTs are more likely to be benign and have a better ...
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
(
MDPI
, 2021 , Article)
Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and
is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle
East and North Africa (MENA) ...
SARS-CoV-2 Infection and Smoking: What is the association? A brief review
(
Elsevier
, 2021 , Article)
Susceptibility to severe illness from COVID-19 is anticipated to be associated with cigarette smoking as it aggravates the risk of cardiovascular and respiratory illness, including infections. This is particularly important ...
Preputial balanitis xerotica obliterans shortly after hand, foot and mouth disease in a 5-year-old boy: Coincidence or consequence?
(
Elsevier
, 2021 , Other)
Balanitis xerotica obliterans (BXO), a genital form of lichen sclerosus (LS) in males, is a progressive, sclerosing, inflammatory dermatosis affecting the foreskin, frenulum, glans penis, meatus, and urethra. BXO was ...
Biased agonism at G protein-coupled receptors
(
Elsevier
, 2021 , Other)
G protein-coupled receptors (GPCRs) represent the largest family of approved therapeutic targets. Ligands stimulating these receptors specifically activate multiple signalling pathways that induce not only the desired ...
The MethodologicAl STandards for Epidemiological Research (MASTER) scale demonstrated a unified framework for bias assessment
(
Elsevier
, 2021 , Article)
Objective: This paper presents a unified framework for assessment of the methodological quality of analytic study designs. Study Design and Setting: A systematic review of 393 methodological quality assessment tools that ...
A proposed framework to guide evidence synthesis practice for meta-analysis with zero-events studies
(
Elsevier
, 2021 , Article)
ObjectiveIn evidence synthesis practice, researchers often face the problem of how to deal with zero-events. Inappropriately dealing with zero-events studies may lead to research waste and mislead healthcare practice. We ...
Abnormal brain structure and behavior in MyD88-deficient mice.
(
Elsevier
, 2021 , Article)
While the original protein Toll in Drosophila melanogaster regulates both host defense and morphogenesis, the role of its ortholog Toll-like receptors (TLRs), the interleukin 1 receptor (IL-1R) family, and the associated ...
Molecular correlates of immune cytolytic subgroups in colorectal cancer by integrated genomics analysis
(
Oxford University Press
, 2021 , Article)
Although immune checkpoint inhibition (ICI) has shown promising results in metastatic dMMR/MSI-H colorectal cancer (CRC), the majority of pMMR/MSS patients do not respond to such therapies. To systematically evaluate the ...
TERT gene fusions characterize a subset of metastatic Leydig cell tumors
(
Elsevier
, 2021 , Article)
Objective: Metastatic Leydig cell tumors (LCT) are rare, difficult to treat malignancies without known underlying molecular-genetic events. An index case of metastatic LCT showed an LDLR-TERT gene fusion upon routine genetic ...