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Soccer-related severe blunt splenic injury in a young goalkeeper
(
Elsevier
, 2021 , Article)
Abdominal injuries are rare in sports, but even minor traumas may result in potentially life-threatening injuries. The most frequent abdominal injury is abdominal wall contusion, following by blunt injuries of the kidneys ...
The role of glycogen synthase kinase 3 (GSK3) in cancer with emphasis on ovarian cancer development and progression: A comprehensive review
(
Association of Basic Medical Sciences of FBIH
, 2021 , Article Review)
Glycogen synthase kinase 3 (GSK3) is a monomeric serine-threonine kinase discovered in 1980 in a rat skeletal muscle. It has been involved in various cellular processes including embryogenesis, immune response, inflammation, ...
Novel nitrogen-based chalcone analogs provoke substantial apoptosis in HER2-positive human breast cancer cells via JNK and ERK1/ERK2 signaling pathways
(
MDPI
, 2021 , Article)
Natural chalcones possess antitumor properties and play a role as inducers of apoptosis, antioxidants and cytotoxic compounds. We recently reported that novel nitrogen chalcone-based compounds, which were generated in our ...
A comprehensive review on the antiviral activities of chalcones
(
Taylor and Francis Ltd.
, 2021 , Article)
Some viral outbreaks have plagued the world since antiquity, including the most recent COVID-19 pandemic. The continuous spread and emergence of new viral diseases have urged the discovery of novel treatment options that ...
Snornas and mirnas networks underlying covid-19 disease severity
(
MDPI
, 2021 , Article)
There is a lack of predictive markers for early and rapid identification of disease progression in COVID-19 patients. Our study aims at identifying microRNAs (miRNAs)/small nucleolar RNAs (snoRNAs) as potential biomarkers ...
The therapeutic effects of adipose-derived mesenchymal stem cells on obesity and its associated diseases in diet-induced obese mice
(
Nature Research
, 2021 , Article)
Obesity is a global public health concern associated with increased risk of several comorbidities. Due to the limited effectiveness of current therapies, new treatment strategies are needed. Our aim was to examine the ...
KYNU, a novel potential target that underpins CD44-promoted breast tumour cell invasion
(
Blackwell Publishing Inc.
, 2021 , Article Review)
Using a validated tetracycline-off-inducible CD44 expression system in mouse model, we have previously demonstrated that the hyaluronan (HA) receptor CD44 promotes breast cancer (BC) metastasis to the liver. To unravel the ...
Research Methods for Zero Event Proportion Studies: The Incidence of Bleeding After Thoracentesis and Tube Thoracostomy in Patients With Uncorrected Coagulopathy
(
Elsevier Inc.
, 2021 , Article)
In a recent meta-analysis published in CHEST (November 2021), Fong et al1 investigated the incidence of bleeding after thoracentesis and tube thoracostomy in patients with uncorrected coagulopathy. The authors used the ...
The epidemic volatility index, a novel early warning tool for identifying new waves in an epidemic
(
Nature Research
, 2021 , Article)
Early warning tools are crucial for the timely application of intervention strategies and the mitigation of the adverse health, social and economic effects associated with outbreaks of epidemic potential such as COVID-19. ...
Distinct genomic features across cytolytic subgroups in skin melanoma.
(
Springer
, 2021 , Article)
Skin melanoma is a highly immunogenic cancer. The intratumoral immune cytolytic activity (CYT) reflects the ability of cytotoxic T and NK cells to eliminate cancer cells, and is associated with improved patient survival. ...