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Molecular Evidence of Anticancer Activity of Camel Milk Combined with Camel Urine
(
Austin Publishing Group
, 2021 , Article)
Camel Milk (CM) and Camel Urine (CU) is a traditional practice in the
Middle East and other countries as an alternative treatment against cancer. We
hypothesized that a combination of CM and CU (CM+CU), used at ...
Soccer-related severe blunt splenic injury in a young goalkeeper
(
Elsevier
, 2021 , Article)
Abdominal injuries are rare in sports, but even minor traumas may result in potentially life-threatening injuries. The most frequent abdominal injury is abdominal wall contusion, following by blunt injuries of the kidneys ...
Novel nitrogen-based chalcone analogs provoke substantial apoptosis in HER2-positive human breast cancer cells via JNK and ERK1/ERK2 signaling pathways
(
MDPI
, 2021 , Article)
Natural chalcones possess antitumor properties and play a role as inducers of apoptosis, antioxidants and cytotoxic compounds. We recently reported that novel nitrogen chalcone-based compounds, which were generated in our ...
Proteomic profile alterations in porcine conceptuses during early stages of development
(
Elsevier
, 2021 , Article)
The dynamic embryo development during the early stages of gestation requires precise molecular changes, including proteomic ones. We aimed to find unique proteins for porcine conceptuses specifically during the peri-implantation ...
Modulation of Neuro-Inflammatory Signals in Microglia by Plasma Prekallikrein and Neuronal Cell Debris
(
Frontiers Media
, 2021 , Article)
Microglia, the resident phagocytes of the central nervous system and one of the key modulators of the innate immune system, have been shown to play a major role in brain insults. Upon activation in response to neuroinflammation, ...
Pharmacological and antioxidant activities of rhus coriaria l. (sumac)
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2021 , Article)
Rhus coriaria L. (Anacardiaceae), commonly known as sumac, is a commonly used spice, condiment, and flavoring agent, especially in the Mediterranean region. Owing to its bountiful beneficial values, sumac has been used in ...
KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals
(
Nature Research
, 2021 , Article)
Regulation of IP3 receptors (IP3Rs) by IP3 and Ca2+ allows regenerative Ca2+ signals, the smallest being Ca2+ puffs, which arise from coordinated openings of a few clustered IP3Rs. Cells express thousands of mostly mobile ...
IDF Diabetes Atlas: Estimation of Global and Regional Gestational Diabetes Mellitus Prevalence for 2021 by International Association of Diabetes in Pregnancy Study Group’s Criteria
(
Elsevier
, 2021 , Article)
AimsThe approaches used to screen and diagnose gestational diabetes mellitus (GDM) vary widely. We generated a comparable estimate of the global and regional prevalence of GDM by International Association of Diabetes in ...
HCV cirrhotic patients treated with direct-acting antivirals: Detection of tubular dysfunction and resolution after viral clearance
(
Wiley-Blackwell
, 2021 , Other)
Bilotti et al's1 recent excellent report on the prevalence of tubular and glomerular dysfunction in patients with HCV infection on direct-acting antiviral (DAA) agents, and their evolution following HCV clearance adds to ...
Targeted and systemic insights into the crosstalk between DNA-dependent protein kinase catalytic subunit and receptors of estrogen, progesterone and epidermal growth factor in the context of cancer
(
Springer
, 2021 , Article)
DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has emerged as a regulator of carcinogenesis. Increased expression of DNA-PKcs correlates with metastatic cancers. Here we review recently reported crosstalk of ...