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Data extraction error in pharmaceutical versus non-pharmaceutical interventions for evidence synthesis: Study protocol for a crossover trial
(
Elsevier
, 2023 , Article)
BackgroundData extraction is the foundation for research synthesis evidence, while data extraction errors frequently occur in the literature. An interesting phenomenon was observed that data extraction error tend to be ...
Role of HMGB1 and its associated signaling pathways in human malignancies
(
Elsevier
, 2023 , Article)
The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal role in promoting both cell death and survival. HMGB1 ...
Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
(
Elsevier
, 2023 , Article)
In a recently published, post-hoc analysis of the hallmark EMPA-REG OUTCOME trial, Kramer ¨ et al.1 assessed whether changes in cardiac and haemodynamic markers achieved with empagliflozin in subjects with type 2 diabetes ...
Clinicopathological and prognostic value of chemokine receptor CCR7 expression in head and neck squamous cell carcinoma: a systematic review and meta-analysis.
(
Taylor and Francis Group
, 2023 , Article)
This study aimed to identify the clinicopathological characteristics and prognostic value of CC chemokine receptor 7 (CCR7) expression in patients with head and neck squamous cell carcinoma (HNSSC). The Preferred Reporting ...
Association of polypharmacy with incidence of CKD: a retrospective cohort study: a letter to the Editor
(
Springer Nature
, 2023 , Other)
Kimura et al.’s recently published report on a retrospective examination of the Fukushima chronic kidney disease (CKD) patient cohort provides an interesting perspective on this rising therapeutic morbidity [1]. The study ...
Validation of Doi's weighted average glucose as a measure of post-load glucose excursion for clinical use.
(
Biomolecules and Biomedicine
, 2023 , Article)
In this study, we examined the performance of a novel index of glucose excursion (Doi’s weighted average glucose [dwAG]) in relation to the conventional measure of area under the oral glucose tolerance test (A-GTT) and the ...
Epidemiology and early bacterial colonization of minor and moderate pediatric burns: A retrospective study from a developing country
(
Elsevier
, 2023 , Article)
ObjectivesInfection is still the leading cause of morbidity and mortality among burn patients worldwide. Isolation and identification of pediatric burn wound bacterial colonizers can prevent infection and improve burn ...
Applications of Artificial Intelligence in Thrombocytopenia
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Thrombocytopenia is a medical condition where blood platelet count drops very low. This drop in platelet count can be attributed to many causes including medication, sepsis, viral infections, and autoimmunity. Clinically, ...
High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
(
Elsevier
, 2023 , Article)
Coronavirus disease 2019 (COVID-19) is an infectious disease caused by SARS-CoV-2, which was first discovered in Wuhan, China. The disease has grown into a global pandemic causing mild to moderate symptoms in most people. ...
ApoM binds endotoxin contributing to neutralization and clearance by High Density Lipoprotein.
(
Elsevier
, 2023 , Article)
HDL possesses anti-inflammatory properties, however, the exact mechanism is not fully understood. Endotoxin is a potent inducers of TLR4 signaling, leading to inflammatory mediators' release. It has been estimated that ...