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Now showing items 141-150 of 189
Population Preferences for Primary Care Models for Hypertension in Karnataka, India
(
American Medical Association
, 2023 , Article)
IMPORTANCE Hypertension contributes to more than 1.6 million deaths annually in India, with many individuals being unaware they have the condition or receiving inadequate treatment. Policy initiatives to strengthen disease ...
Exploring the Role of microRNAs in Glioma Progression, Prognosis, and Therapeutic Strategies
(
MDPI
, 2023 , Article)
Gliomas, which arise from glial cells in the brain, remain a significant challenge due to their location and resistance to traditional treatments. Despite research efforts and advancements in healthcare, the incidence of ...
Barriers and facilitators of older adults for professional mental health help-seeking: a systematic review
(
BioMed Central Ltd
, 2023 , Article)
Background: Older adults are at an increased risk for mental health issues, yet they are less likely to seek professional help. This systematic review aims to identify and summarize literature on the barriers and facilitators ...
Determination of Medicago orbicularis Antioxidant, Antihemolytic, and Anti-Cancerous Activities and Its Augmentation of Cisplatin-Induced Cytotoxicity in A549 Lung Cancer Cells
(
MDPI
, 2023 , Article)
The anti-lung cancer properties of the plant Medicago orbicularis have not been explored yet. Therefore, we identified its phytochemical composition and investigated the antioxidant, anti-hemolytic, and anti-cancerous ...
Regulatory enforcement of the marketing of fixed-dose combinations in India: a case study of systemic antibiotics
(
Springer Nature
, 2023 , Article)
Background: In India, states have licensed the manufacture of large numbers of fixed-dose combination (FDC) drugs without the required prior approval of the central regulator. This paper describes two major regulatory ...
Integrating AI and ML in Myelodysplastic Syndrome Diagnosis: State-of-the-Art and Future Prospects
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Myelodysplastic syndrome (MDS) is composed of diverse hematological malignancies caused by dysfunctional stem cells, leading to abnormal hematopoiesis and cytopenia. Approximately 30% of MDS cases progress to acute myeloid ...
The role of anti-Mullerian hormone and other correlates in patients with polycystic ovary syndrome
(
Taylor and Francis Ltd.
, 2023 , Article)
Background
Anti-Müllerian hormone (AMH) has recently emerged as a promising biomarker for the detection of polycystic ovarian morphology. In polycystic ovary syndrome (PCOS), an elevated level of AMH has been suggested ...
An Updated Review of the Biomarkers of Response to Immune Checkpoint Inhibitors in Merkel Cell Carcinoma: Merkel Cell Carcinoma and Immunotherapy
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Merkel cell carcinoma (MCC) is primarily a disease of the elderly Caucasian, with most cases occurring in individuals over 50. Immune checkpoint inhibitors (ICI) treatment has shown promising results in MCC patients. ...
Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
(
MDPI
, 2023 , Article)
Calmodulin (CaM) is a small, multifunctional calcium (Ca2+)-binding sensor that binds and regulates the open probability of cardiac ryanodine receptor 2 (RyR2) at both low and high cytosolic Ca2+ concentrations. Recent ...
Maternal depressiveness and infant growth outcomes: Findings from the MAASTHI cohort study in India
(
Elsevier
, 2023 , Article)
ObjectiveThe study aims to examine the association between depressiveness in mothers on infant obesity and stunting at one year of age. MethodsWe enrolled 4829 pregnant women, followed them up at public health facilities ...