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Now showing items 161-170 of 304
Phospholipase C zeta and calcium oscillations at fertilisation: The evidence applications and further questions
(
Elsevier Ltd
, 2018 , Article)
Oocyte activation is a fundamental event at mammalian fertilisation, initiated by a series of characteristic calcium (Ca2+) oscillations in mammals. This characteristic pattern of Ca2+ release is induced in a species-specific ...
The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications
(
Frontiers Media S.A.
, 2021 , Article)
Diabetes mellitus is a major debilitating disease whose global incidence is progressively increasing with currently over 463 million adult sufferers and this figure will likely reach over 700 million by the year 2045. It ...
Nanotoxicology of dendrimers in the mammalian heart: Ex vivo and in vivo administration of g6 pamam nanoparticles impairs recovery of cardiac function following ischemia-reperfusion injury
(
Dove Medical Press Ltd.
, 2020 , Article)
Aim: The effects of polyamidoamine (PAMAM) dendrimers on the mammalian heart are not completely understood. In this study, we have investigated the effects of a sixth-generation cationic dendrimer (G6 PAMAM) on cardiac ...
In honour of Professor Jackie Ying, recipient of the Journal of Drug Targeting's Lifetime Achievement Award�for 2020
(
Taylor and Francis Ltd
, 2020 , Article)
[No abstract available]
In honour of Professor Patrick Couvreur, recipient of the Journal Of Drug Targeting?s Lifetime Achievement Award For 2019
(
Taylor and Francis Ltd
, 2019 , Article)
[No abstract available]
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
(
Taylor and Francis Ltd
, 2020 , Article)
Objectives: Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize ...
Glycosylation is a novel TGF?1-independent post-translational modification of Smad2
(
Elsevier B.V.
, 2019 , Article)
Smad2 is a crucial component of intracellular signaling by transforming growth factor-? (TGF?). Here we describe that Smad2 is glycosylated, which is a novel for Smad2 post-translational modification. We showed that the ...
Flight Versus Ground Out-of-hospital Rapid Sequence Intubation Success: a Systematic Review and Meta-analysis
(
Taylor and Francis Ltd
, 2018 , Article)
Introduction: Endotracheal intubation (ETI) is a critical procedure performed by both air medical and ground based emergency medical services (EMS). Previous work has suggested that ETI success rates are greater for air ...
Immunogenicity after pre- and post-exposure rabies vaccination: A systematic review and dose-response meta-analysis
(
Elsevier
, 2021 , Article)
There are a myriad of vaccine schedules for rabies pre- (PrEP) and post-exposure prophylaxis (PEP) that differ in the number and timedoses, number of visits, length of schedule, and route of administration. The objective ...
Sleep problems in adolescence and overweight/obesity in young adults: is there a causal link?
(
Elsevier
, 2018 , Article)
This study aims to explore if there is a causal association between adolescence sleep problems and overweight/obesity (Ow/Ob) in young adults. Youth self-reports were used to explore if adolescence (mean age 13.90 years, ...