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Integrated health system intervention aimed at reducing type 2 diabetes risk in women after gestational diabetes in South Africa (IINDIAGO): A randomised controlled trial protocol
(
BMJ Publishing Group
, 2024 , Article)
Introduction South Africa has a high prevalence of gestational diabetes mellitus (GDM; 15%) and many of these women (48%) progress to type 2 diabetes mellitus (T2DM) within 5 years post partum. A significant proportion ...
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
(
Elsevier B.V.
, 2024 , Article)
The unfolded protein response (UPR) detects increased misfolded proteins and activates protein refolding, protein degradation and inflammatory responses. UPR sensors in the endoplasmic reticulum, IRE1α and PERK, bind and ...
Pre-prandial plasma liver-expressed antimicrobial peptide 2 (LEAP2) concentration in humans is inversely associated with hunger sensation in a ghrelin independent manner
(
Springer Science and Business Media Deutschland GmbH
, 2023 , Article)
Purpose
The liver-expressed antimicrobial peptide 2 (LEAP2) is a newly recognized peptide hormone that acts via the growth hormone secretagogue receptor (GHSR) blunting the effects of ghrelin and displaying ghrelin-independent ...
Corrigendum to “Morphometric study of the facial skeleton in Jordanians: A computed tomography scan-based study” [Forensic Sci. Int. 302 (2019) 109916] (Forensic Science International (2019) 302, (S0379073819303287), (10.1016/j.forsciint.2019.109916))
(
Elsevier Ireland Ltd
, 2020 , Article)
The authors regret that the affiliation published for Dr. Mohammed Allouh and Heba شis incorrect. The affiliation for Dr. Mohammed Allouh should be: Faculty of Medicine, Jordan University of Science and Technology, Irbid, ...
Breast lump as the initial presentation of metastatic uterine leiomyosarcoma: a case report and comprehensive literature review
(
Medicinska Naklada Zagreb
, 2024 , Article)
Uterine leiomyosarcoma (uLMS) is a rare but aggressive cancer with a high metastatic potential and an unfavo-rable prognosis. A 54-year-old woman with a history of uterine fibroids clinically presented with a painless, ...
A Pilot Randomized Controlled Trial of De Novo Belatacept-based Immunosuppression After Lung Transplantation.
(
Wolters Kluwer Health
, 2024 , Article)
Chronic lung allograft dysfunction (CLAD) is the leading cause of death beyond the first year after lung transplantation. The development of donor-specific antibodies (DSA) is a recognized risk factor for CLAD. Based on ...
Determining the conclusiveness of a meta-analysis.
(
Wolters Kluwer Health
, 2024 , Article)
The pursuit of conclusive evidence related to an unanswered foreground (decision-making) question has been the driving factor behind multiple ongoing and planned randomized controlled trials as well as meta-analyses. ...
Comparison of bias adjustment in meta-analysis using data-based and opinion-based methods.
(
Wolters Kluwer Health
, 2024 , Article)
Several methods exist for bias adjustment of meta-analysis results, but there has been no comprehensive comparison with unadjusted methods. We compare 6 bias-adjustment methods with 2 unadjusted methods to examine how these ...
Interruption of perivascular and perirenal adipose tissue thromboinflammation rescues prediabetic cardioautonomic and renovascular deterioration
(
Portland Press Ltd
, 2024 , Article)
The cardiovascular and renovascular complications of metabolic deterioration are associated with localized adipose tissue dysfunction. We have previously demonstrated that metabolic impairment delineated the heightened ...
Efficacy and Clinical Outcomes of mRNA COVID-19 Vaccine in Pregnancy: A Systematic Review and Meta-Analysis
(
S. Karger AG
, 2024 , Article)
BACKGROUND: The world has witnessed one of the largest pandemics, dubbed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of December 2020, the USA alone reported 98,948 cases of coronavirus disease 2019 ...