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The Combination of Dasatinib and PD L1 inhibitor prevents the progression of epithelial mesenchymal transition and dramatically blocks cell invasion of HER2 positive breast cancer cells
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Qatar University Press
, 2021 , Poster)
Introduction: Both Dasatinib (DA), a tyrosine kinase inhibitor that is used for targeted cancer therapy, and programmed death-ligand 1 (PD-1/PD-L1) inhibitor that is an immune checkpoint therapy, play a vital role in the ...
Homozygous mutation in MCM7 causes autosomal recessive primary microcephaly and intellectual disability
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BMJ Publishing Group
, 2021 , Article)
Minichromosomal maintenance (MCM) complex components 2, 4, 5 and 6 have been linked to human disease with phenotypes including microcephaly and intellectual disability. The MCM complex has DNA helicase activity and is ...
A Rare Sequela of Constriction Band Syndrome: Case Report.
(
Lippincott, Williams & Wilkins
, 2021 , Report)
The patient in this case report is a 19-year-old man who presented with left foot cauliflower lesion. He complained of an inability to wear proper shoes, in addition to an unpleasant appearance of his foot. The lesion was ...
Quality of life, sleep quality, depression, anxiety, stress, eating habits, and social bounds in nurses during the coronavirus disease 2019 pandemic in qatar (The PROTECTOR study): A cross-sectional, comparative study
(
MDPI
, 2021 , Article)
There have been numerous concerns regarding the physical and mental health of nurses during the COVID-19 pandemic. Stress, sleep deprivation, anxiety, and depression potentiated nurses’ vulnerability to poor eating habits. ...
An Early Warning Tool for Predicting Mortality Risk of COVID-19 Patients Using Machine Learning
(
Springer
, 2021 , Article)
COVID-19 pandemic has created an extreme pressure on the global healthcare services. Fast, reliable, and early clinical assessment of the severity of the disease can help in allocating and prioritizing resources to reduce ...
A proposed framework to guide evidence synthesis practice for meta-analysis with zero-events studies
(
Elsevier
, 2021 , Article)
ObjectiveIn evidence synthesis practice, researchers often face the problem of how to deal with zero-events. Inappropriately dealing with zero-events studies may lead to research waste and mislead healthcare practice. We ...
Methodological issues of systematic reviews and meta-analyses in the field of sleep medicine: A meta-epidemiological study
(
Elsevier
, 2021 , Article)
An increasing number of systematic reviews and meta-analyses (SRMAs) have been published in the field of sleep medicine. We evaluated the methodological issues of these SRMAs. A protocol was developed in advance. Three ...
Isolated deep orbital hemangioma treated successfully with oral propranolol in a 2-month-old infant: Case report with literature review
(
Elsevier
, 2021 , Article)
Purpose
Infantile hemangiomas (IH) are the most common benign vascular tumors of infancy. Ocular complications due to orbital IH include strabismal, deprivational, or anisometropic astigmatism, and visual loss secondary ...
Association between pre-existing conditions and hospitalization, intensive care services and mortality from COVID-19 - a cross sectional analysis of an international global health data repository
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Qatar University Press
, 2021 , Poster)
Objective: To investigate the association between pre-existing conditions and hospitalization, need for intensive care services (ICU) and mortality due to COVID-19. Methods: We used data on all cases recorded in the Global ...
Barriers and Facilitators to Mental Health Help-seeking among Older Adults: A Systematic Review
(
Qatar University Press
, 2021 , Poster)
Background: Older adults are very unlikely to seek mental health help. There are multiple factors that contribute to a person's final decision to seek formal help. The aim of this study is to systematically review and ...