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An Updated Review of the Biomarkers of Response to Immune Checkpoint Inhibitors in Merkel Cell Carcinoma: Merkel Cell Carcinoma and Immunotherapy
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
Merkel cell carcinoma (MCC) is primarily a disease of the elderly Caucasian, with most cases occurring in individuals over 50. Immune checkpoint inhibitors (ICI) treatment has shown promising results in MCC patients. ...
Epidemiology and early bacterial colonization of minor and moderate pediatric burns: A retrospective study from a developing country
(
Elsevier
, 2023 , Article)
ObjectivesInfection is still the leading cause of morbidity and mortality among burn patients worldwide. Isolation and identification of pediatric burn wound bacterial colonizers can prevent infection and improve burn ...
The correlation between ureteric orifice morphology and primary vesicoureteral reflux grade and the impact on the effectiveness of endoscopic reflux correction
(
Elsevier
, 2023 , Article)
IntroductionEarly diagnosis and treatment of primary vesicoureteral reflux (VUR) are essential for preserving renal function. ObjectivesThe study explored whether preoperative cystoscopic grading of refluxing ureteric ...
Bilateral adnexal masses: A case report of acute myeloid leukemia presenting with myeloid sarcoma of the ovary and review of literature
(
Elsevier
, 2023 , Article)
Here, we report a case of myeloid sarcoma (extramedullary myeloid tumor) of the left ovary in a female with known acute myeloid leukemia (AML), who was discovered to have bilateral adnexal masses during treatment planning ...
Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways.
(
Springer Nature
, 2024 , Article)
Recent investigations have reported the benefits of using a tyrosine kinase inhibitor, dasatinib (DA), as well as programmed death-ligand 1 (PD-L1) inhibitors in the management of several solid tumors, including breast ...
The Frequency, Severity, and Risk Factors of Hickman Catheter-Related Complications in Pediatric Cancer Patients: A Single-Center Experience from Bosnia and Herzegovina
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AVES
, 2024 , Article)
Objective: This study aimed to identify the frequency, severity, and risk factors associated with Hickman catheter-related complications in children with hemato-oncological malignancies at the largest pediatric tertiary ...
Assay-agnostic spatial profiling detects tumor microenvironment signatures: new diagnostic insights for triple-negative breast cancer
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John Wiley and Sons Ltd
, 2023 , Article)
The role of the tumor microenvironment (TME) in immuno-oncology has driven demand for technologies that deliver in situ, or spatial, molecular information. Compartmentalized heterogeneity that traditional methods miss is ...
The Role of Demographic and Clinical Characteristics in Distinguishing Testicular Torsion from Torsion of the Appendix Testis: A Single-center Retrospective Study
(
Karolinum - Nakladatelstvi Univerzity Karlovy
, 2023 , Article)
The acute scrotum (AS) in the pediatric population is a medical emergency. AS is usually caused by testicular torsion (TT) and torsion of the appendix testis (TAT). The current study explored which demographic and clinical ...
Proteomic Profiling of Small-Cell Lung Cancer: A Systematic Review
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
The accurate diagnosis of small-cell lung cancer (SCLC) is crucial, as treatment strategies differ from those of other lung cancers. This systematic review aims to identify proteins differentially expressed in SCLC compared ...
The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer
(
Elsevier
, 2023 , Article)
IntroductionHER-2/neu is a protein present on the surface of specific cancer cells and has been linked to the development and progression of certain cancer types. It is present in 15 to 20% of breast cancers and is clinically ...