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Interleukin-4 and interleukin-13 evoke scratching behaviour in mice
(
Blackwell Publishing Ltd
, 2019 , Article)
Persistent and relapsing itch commonly manifests in inflammatory skin disorders such as atopic dermatitis (AD). AD pathogenesis is driven by interleukin-4 (IL-4) and interleukin-13 (IL-13). Dupilumab, a monoclonal antibody ...
Protein expression profiling identifies key proteins and pathways involved in growth inhibitory effects exerted by guggulsterone in human colorectal cancer cells
(
MDPI AG
, 2019 , Article)
Colorectal cancer (CRC) is a leading killer cancer worldwide and one of the most common malignancies with increasing incidences of mortality. Guggulsterone (GS) is a plant sterol used for treatment of various ailments such ...
Understanding the Burden of Atopic Dermatitis in Africa and the Middle East
(
Springer Healthcare
, 2019 , Article Review)
Atopic dermatitis (AD) is a common inflammatory skin disease characterized by intensely pruritic lesions. The prevalence of atopic dermatitis is increasing in developing regions, including Africa and the Middle East. ...