Medicine Research: المرسلات الحديثة
السجلات المعروضة 61 -- 80 من 1891
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Artificial intelligence in airway management: A systematic review and meta-analysis
( Elsevier , 2025 , Article)BackgroundAirway management is the cornerstone of anesthesia care. Complications of difficult airways are usually fatal to patients. Artificial intelligence (AI) has shown promising results in enhancing clinicians' performance ... -
A prospective cluster randomized trial of an interventions bundle to reduce inappropriate antibiotic use for upper respiratory tract infections in the outpatient setting
( Springer Nature , 2025 , Article)Background: Antibiotic overuse and increasing antimicrobial resistance are global public health threats. We determined the impact of a multicomponent intervention in reducing inappropriate antibiotic use for upper respiratory ... -
A deep dive into the surgical and pharmacological considerations of obesity in chronic myeloid leukemia: a narrative review
( Lausanne Frontiers Media , 2025 , Article)Background/Objectives: The rising prevalence of obesity presents significant challenges in managing chronic myeloid leukemia (CML). Bariatric surgery alters the bioavailability of oral medications, necessitating tailored ... -
Acute and chronic graft-versus-host disease treatment and management in the Eastern Mediterranean region: A Worldwide Network for Blood and Marrow Transplantation survey
( Elsevier , 2025 , Article)BACKGROUND: The treatment of acute and chronic graft-versus-host disease (GvHD) remains a challenge, particularly in cases of steroid-refractory GvHD. The management of GvHD varies between institutions, and little is known ... -
A “True Lifecycle Approach” towards governing healthcare AI with the GCC as a global governance model
( Springer Nature , 2025 , Article)This paper proposes a “True Lifecycle Approach” (TLA) towards governing healthcare AI. The TLA governance model embeds core healthcare law principles—like informed consent, liability, and patient rights—throughout AI’s ... -
Advancing explainable AI in healthcare: Necessity, progress, and future directions
( Elsevier , 2025 , Article)Clinicians typically aim to understand the shape of the liver during treatment planning that could potentially minimize any harm to the surrounding healthy tissues and hepatic vessels, thus, constructing a precise geometric ... -
Advancements in decoy oligodeoxynucleotides targeting STAT3 and STAT5 for cancer therapy
( Elsevier , 2025 , Article)The Signal Transducer and Activator of Transcription (STAT) proteins are a group of cytoplasmic transcription factors. This group comprises seven members, named STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6. These ... -
A Novel PLCζ Mutation Linked to Male Factor Infertility Induces a Gain-of-Function Effect on Ca2+ Oscillations in Eggs
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Mammalian fertilization is triggered by a series of calcium (Ca2+) oscillations that are essential for egg activation and successful embryo development. It is widely accepted that Phospholipase C zeta (PLCζ) is the ... -
Adult Sexual Function Following Hypospadias Repair in Childhood: A Systematic Review and Meta-analysis of Long-term Patient Outcomes
( Elsevier , 2025 , Article)ObjectiveTo synthesize and quantitatively analyze available evidence regarding sexual function in adults who underwent hypospadias repair during childhood. MethodsA systematic review and meta-analysis were conducted based ... -
A rare case of perforated giant mesenteric fibromatosis causing acute peritonitis
( Oxford University Press , 2025 , Article)Desmoid tumors (DT) are rare benign tumors originating from myofibroblasts in the mesentery. Although benign, DTs exhibit local invasion and recurrence and may present sporadically or with familial adenomatous polyposis ... -
Arabic Translation and Validation of the Adult Oral Health Standard Set Questionnaire
( Elsevier , 2025 , Article)IntroductionThe Adult Oral Health Standard Set (AOHSS) questionnaire was developed by the International Dental Federation (FDI) and the Oral Adult Health Working Group (OHWG) for oral health assessment in clinical settings, ... -
Acute adult supraglottitis: Difficult intubation & potential airway loss
( Elsevier , 2023 , Article)Acute Adult Supraglottitis (AAS), formerly called epiglottitis, can lead to life-threatening inflammatory oedema of the epiglottis and adjacent structures resulting in constriction of the airway directly over the vocal ... -
The efficacy and safety of venous thromboembolism prophylaxis among hospitalized cirrhotic patients: Systematic review and meta-analysis
( Elsevier , 2025 , Article)Background and study aimsThis meta-analysis aims to evaluate the effect of prophylactic anticoagulation on incidence of venous thromboembolism (VTE), bleeding events, and mortality in hospitalized cirrhotic patients. ... -
Defective ryanodine receptor N-terminus inter-subunit interaction is a common mechanism in neuromuscular and cardiac disorders
( Frontiers Media , 2022 , Article)The ryanodine receptor (RyR) is a homotetrameric channel mediating sarcoplasmic reticulum Ca<sup>2+</sup> release required for skeletal and cardiac muscle contraction. Mutations in RyR1 and RyR2 lead to life-threatening ... -
Disparate molecular mechanisms in cardiac ryanodine receptor channelopathies
( Frontiers Media , 2024 , Article)Aims: Mutations in the cardiac ryanodine receptor (RyR2) are associated with catecholaminergic polymorphic ventricular tachycardia (CPVT). This study investigates the underlying molecular mechanisms for CPVT mutations ... -
The 6th Qatar International Internal Medicine (6-QIIM) Conference 2025: Enhancing patient care through regional and international collaboration and innovation
( HBKU Press , 2025 , Other)Internal Medicine has witnessed remarkable advancements in recent years, encompassing telemedicine, personalized medicine, and artificial intelligence. However, significant challenges persist. Noncommunicable diseases such ... -
Microneedle Delivery of Heterologous Microparticulate COVID-19 Vaccine Induces Cross Strain Specific Antibody Levels in Mice
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Background: In recent years, the COVID-19 pandemic has significantly impacted global health, largely driven by the emergence of various genetic mutations within the SARS-CoV-2 virus. Although the pandemic phase has passed, ... -
Impact of polypharmacy phenogroups on different heart failure phenotypes in patients with chronic heart failure: a retrospective examination of real-world cohort
( Frontiers Media S.A. , 2025 , Article)Background: Polypharmacy is a rising morbidity amongst patients with chronic heart failure (CHF), with reported prevalence ranging from 70% to 85%. While polypharmacy is essential for managing comorbid conditions, its exact ... -
Gum Acacia supplementation improves adiponectin levels and HbA1c/adiponectin ratio in women with type 2 diabetes: A randomized controlled trial
( Functional Food Center Inc. , 2025 , Article)Background: Adiponectin contributes to the regulation of glucose homeostasis and lipid profiles and plays a role in maintaining average body weight. At high serum concentrations, adiponectin sensitizes cells to insulin and ... -
Rethinking the Diagnosis and Management of Antibody-Mediated Rejection in Multidisciplinary Transplant Meetings: A Global Survey and Banff Working Group Recommendations
( John Wiley & Sons , 2025 , Article)Introduction: The diagnosis of antibody-mediated rejection (AMR) requires input from several transplant professionals. Bringing clinical and laboratory experts together may help standardize care. Yet, little is known about ...