Medicine Research: المرسلات الحديثة
السجلات المعروضة 801 -- 820 من 1819
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An Introduction to the Special Issue “Protein Glycation in Food, Nutrition, Health and Disease”
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)On 20–24 September 2021, leading researchers in the field of glycation met online at the 14th International Symposium on the Maillard Reaction (IMARS-14), hosted by the authors of this introductory editorial, who are from ... -
Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders
( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is an adipocytokine with several intriguing properties. It was first identified as pre-B-cell colony-enhancing factor but turned out to possess enzymatic functions ... -
Taxonomy of communications in the operating room
( Springer Verlag , 2018 , Conference)US hospitals are facing critical problems of nurse shortage. One report predicts that there will be a shortage of 260,000 registered nurses by 2025 in the USA, and it was found out that patient mortality risk is 6% higher ... -
Prevalence and potential determinants of covid-19 vaccine hesitancy and resistance in qatar: Results from a nationally representative survey of qatari nationals and migrants between december 2020 and january 2021
( MDPI AG , 2021 , Article)Global COVID-19 pandemic containment necessitates understanding the risk of hesitance or resistance to vaccine uptake in different populations. The Middle East and North Africa currently lack vital representative vaccine ... -
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
( MDPI , 2022 , Article)Variants in cardiac myosin-binding protein C (cMyBP-C) are the leading cause of inherited hypertrophic cardiomyopathy (HCM), demonstrating the key role that cMyBP-C plays in the heart’s contractile machinery. To investigate ... -
A novel deep learning technique for morphology preserved fetal ECG extraction from mother ECG using 1D-CycleGAN
( Elsevier , 2024 , Article)The non-invasive fetal electrocardiogram (fECG) enables easy detection of developing heart abnormalities, leading to a significant reduction in infant mortality rate and post-natal complications. Due to the overlapping of ... -
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals over 10 months
( Elsevier , 2023 , Article)BackgroundEvidence on the effectiveness of vaccination-induced immunity compared to SARS-CoV-2 natural immunity is warranted to inform vaccination recommendations. AimIn this study, we aimed to conduct a comparative ... -
Glycomic and Glycoproteomic Techniques in Neurodegenerative Disorders and Neurotrauma: Towards Personalized Markers
( MDPI , 2022 , Article Review)The proteome represents all the proteins expressed by a genome, a cell, a tissue, or an organism at any given time under defined physiological or pathological circumstances. Proteomic analysis has provided unparalleled ... -
Synthesis of New Chromene Derivatives Targeting Triple-Negative Breast Cancer Cells
( MDPI , 2023 , Article)Breast cancer continues to be the leading cause of cancer-related deaths among women worldwide. The most aggressive type of breast cancer is triple-negative breast cancer (TNBC). Indeed, not only does TNBC not respond well ... -
Reactive oxygen species: Modulators of phenotypic switch of vascular smooth muscle cells
( MDPI , 2020 , Article Review)Reactive oxygen species (ROS) are natural byproducts of oxygen metabolism in the cell. At physiological levels, they play a vital role in cell signaling. However, high ROS levels cause oxidative stress, which is implicated ... -
Cardiac autonomic neuropathy: A progressive consequence of chronic low-grade inflammation in type 2 diabetes and related metabolic disorders
( MDPI , 2020 , Article Review)Cardiac autonomic neuropathy (CAN) is one of the earliest complications of type 2 diabetes (T2D), presenting a silent cause of cardiovascular morbidity and mortality. Recent research relates the pathogenesis of cardiovascular ... -
Disease-Associated Regulation of Non-Coding RNAs by Resveratrol: Molecular Insights and Therapeutic Applications
( Frontiers Media S.A. , 2022 , Article Review)There have been significant advances, particularly over the last 20 years, in the identification of non-coding RNAs (ncRNAs) and their pathophysiological role in a wide range of disease states, particularly cancer and other ... -
Retinoids and Reactive Oxygen Species in Cancer Cell Death and Therapeutics
( Springer Nature , 2022 , Book chapter)Retinoids are a large family of structurally related natural and synthetic molecules that exhibit a variety of effects in embryogenesis and adult life. The parent compound of retinoids is vitamin A which was first discovered ... -
Towards the Pharmacological Validation and Phytochemical Profiling of the Decoction and Maceration of Bruguiera gymnorhiza (L.) Lam.-A Traditionally Used Medicinal Halophyte
( MDPI , 2022 , Article)Decoctions (leaves and roots) of Bruguiera gymnorhiza (L.) Lam. are traditionally used against diabetes in many countries, including Mauritius. This study endeavoured to evaluate the inhibitory potential of leaves, roots, ... -
Mitochondrial dysfunction and chronic inflammation in polycystic ovary syndrome
( MDPI , 2021 , Article Review)Polycystic ovarian syndrome (PCOS) is the most common endocrine–metabolic disorder affecting a vast population worldwide; it is linked with anovulation, mitochondrial dysfunctions and hormonal disbalance. Mutations in mtDNA ... -
Therapeutic potential of resveratrol in covid-19-associated hemostatic disorders
( MDPI , 2021 , Article)Coagulation disorders, endotheliopathy and inflammation are the most common hallmarks in SARS-CoV-2 infection, largely determining COVID-19's outcome and severity. Dysfunctions of endothelial cells and platelets are tightly ... -
Effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon
( MDPI , 2021 , Article)Objective: This study was designed to determine the efficacy of ivermectin, an FDA-approved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 among asymptomatic subjects that tested positive ... -
Ace2 is an adjacent element of atherosclerosis and covid-19 pathogenesis
( MDPI , 2021 , Article Review)COVID-19 is a highly contagious new infection caused by the single-stranded RNA SarsCoV-2 virus. For the first time, this infection was recorded in December 2019 in the Chinese province of Wuhan. The virus presumably crossed ... -
Retraction to: Samaha et al. effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon. viruses 2021, 13, 989
( MDPI , 2021 , Other)The journal retracts the article, Effects of a Single Dose of Ivermectin on Viral and Clinical Outcomes in Asymptomatic SARS-CoV-2 Infected Subjects: A Pilot Clinical Trial in Lebanon [1], cited above. Following publication, ... -
Vascular inflammation: Players and modulators
( Bentham Science Publishers , 2021 , Article)-