Medicine Research: Recent submissions

Now showing items 401-420 of 1518

    • GPER Acts Through the cAMP/Epac/JNK/AP-1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells 

      Fardoun, Manal; Nasser, Suzanne A.; El-Yazbi, Ahmed F.; Eid, Ali H. ( Wolters Kluwer Health , 2023 , Article)
      Raynaud's phenomenon, which results from exaggerated cold-induced vasoconstriction, is more prevalent in females than males. We previously showed that estrogen increases the expression of alpha 2C-adrenoceptors (α2C-AR), ...

    • Cohort profile: maternal antecedents of adiposity and studying the transgenerational role of hyperglycaemia and insulin (MAASTHI) 

      Lobo, Eunice; Ana, Yamuna; Deepa, R.; Shriyan, Prafulla; Sindhu, N. D.; ... more authors ( BMJ , 2022 , Article)
      Purpose The Maternal Antecedents of Adiposity and Studying the transgenerational role of Hyperglycaemia and Insulin cohort in Bengaluru, South India, aims to understand the transgenerational role of increased circulating ...

    • Vulnerable newborn types: analysis of subnational, population-based birth cohorts for 541 285 live births in 23 countries, 2000–2021 

      Erchick, D. J.; Hazel, E. A.; Katz, J.; Lee, A. C.C.; Diaz, M.; ... more authors ( Wiley , 2023 , Article)
      Objective: To examine prevalence of novel newborn types among 541 285 live births in 23 countries from 2000 to 2021. Design: Descriptive multi-country secondary data analysis. Setting: Subnational, population-based birth ...

    • Global Burden of Cardiovascular Diseases and Risks, 1990-2022 

      George A., Mensah; Fuster, Valentin; Murray, Christopher J.L.; Roth, Gregory A.; Mensah, George A.; ... more authors ( Elsevier , 2023 , Other)
      The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) is a multinational collaborative research study with >10,000 collaborators around the world. GBD generates a time series of summary measures of health, ...

    • Are advertising policies affirmative in restricting the marketing of foods high in fat, salt and sugar (HFSS) in India?: Evidence from SWOT Analysis 

      Shalini, Bassi; Bahl, Deepika; Gopal, Sanjana; Sethi, Vani; Backholer, Kathryn; ... more authors ( Elsevier , 2023 , Article)
      The regulatory Indian environment for advertising high fat, salt, and sugar (HFSS) foods and non-alcoholic beverages, on various media was reviewed. Identified national-level policies were categorised as mandatory or ...

    • How do tobacco control policies work in low-income and middle-income countries? A realist synthesis 

      Hebbar, Pragati Bhaskar; Dsouza, Vivek; Bhojani, Upendra; Prashanth, Nuggehalli Srinivas; Van Schayck, Onno C.P.; ... more authors ( BMJ , 2022 , Article)
      Background The burden of tobacco use is disproportionately high in low- and middle-income countries (LMICs). There is scarce theorisation on what works with respect to implementation of tobacco control policies in these ...

    • Population Preferences for Primary Care Models for Hypertension in Karnataka, India 

      Leslie, Hannah H.; Babu, Giridhara R.; Saldanha, Nolita Dolcy; Turcotte-Tremblay, Anne Marie; Ravi, Deepa; ... more authors ( American Medical Association , 2023 , Article)
      IMPORTANCE Hypertension contributes to more than 1.6 million deaths annually in India, with many individuals being unaware they have the condition or receiving inadequate treatment. Policy initiatives to strengthen disease ...

    • Book review: food and brain health 

      Mohammed, Sawsan; Qoronfleh, M. Walid ( Wolters Kluwer , 2023 , Book Review)
      In 2014, a book entitled “Food and Brain Health” was published by a reputable US-based publisher Nova Science Publishers, Inc, New York. The book is authored and edited by a group of scientists, Dr Musthafa Mohamed Essa ...

    • A Perspective on Patient Safety Culture among Nurses in Qatar 

      Qoronfleh, M. Walid; Essa, Musthafa Mohamed; Mohammed, Sawsan ( Wolters Kluwer , 2023 , Article)
      Background: The vitality of developing a safety culture in healthcare settings has become increasingly important following international investigations that highlighted the failures in health care delivery. Nurses, being ...

    • Proteomic Profiling of Small-Cell Lung Cancer: A Systematic Review 

      Elshoeibi, Amgad Mohamed; Elsayed, Basel; Kaleem, Muhammad Zain; Elhadary, Mohamed Ragab; Abu-Haweeleh, Mohannad Natheef; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)
      The accurate diagnosis of small-cell lung cancer (SCLC) is crucial, as treatment strategies differ from those of other lung cancers. This systematic review aims to identify proteins differentially expressed in SCLC compared ...

    • An Updated Review of the Biomarkers of Response to Immune Checkpoint Inhibitors in Merkel Cell Carcinoma: Merkel Cell Carcinoma and Immunotherapy 

      Fojnica, Adnan; Ljuca, Kenana; Akhtar, Saghir; Gatalica, Zoran; Vranic, Semir ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)
      Merkel cell carcinoma (MCC) is primarily a disease of the elderly Caucasian, with most cases occurring in individuals over 50. Immune checkpoint inhibitors (ICI) treatment has shown promising results in MCC patients. ...

    • Regulatory enforcement of the marketing of fixed-dose combinations in India: a case study of systemic antibiotics 

      Brhlikova, Petra; Mehta, Aashna; McGettigan, Patricia; Pollock, Allyson M.; Roderick, Peter; ... more authors ( Springer Nature , 2023 , Article)
      Background: In India, states have licensed the manufacture of large numbers of fixed-dose combination (FDC) drugs without the required prior approval of the central regulator. This paper describes two major regulatory ...

    • Biomaterials in Traumatic Brain Injury: Perspectives and Challenges 

      Aqel, Sarah; Al-Thani, Najlaa; Haider, Mohammad Z.; Abdelhady, Samar; Al Thani, Asmaa A.; ... more authors ( MDPI , 2023 , Article Review)
      Traumatic brain injury (TBI) is a leading cause of mortality and long-term impairment globally. TBI has a dynamic pathology, encompassing a variety of metabolic and molecular events that occur in two phases: primary and ...

    • The Association Between Short Sleep Duration and Metabolic Syndrome: A Case-Control Study 

      Elshoeibi, Amgad Mohamed; Akomolafe, Aishat; Al-Khulaifi, Aisha; Metwally, Omar; Al-Khayarin, Roudah; ... more authors ( Dove Press Ltd , 2023 , Article)
      Purpose: Short sleep duration and quality are increasingly common in the Middle East and North Africa (MENA) region and has been linked to metabolic syndrome, which increases the risk of cardiovascular disease and diabetes. ...

    • The role of Rezum in the management of refractory urinary retention due to benign prostate hyperplasia: A literature review 

      Khalil ,Ibrahim A.; Aldeeb ,Maya; Mohammed ,Ahmed; Awad ,Khalid; Ibrahim ,Tarek; ... more authors ( Taylor and Francis Ltd. , 2023 , Article)
      Background: Benign prostatic hyperplasia is the most common cause of urinary retention in men (BPH). The gold standard surgical treatment is transurethral resection of the prostate (TURP). However, due to the morbidity and ...

    • The impact of a universal social emotional intervention on students' mental wellbeing in a secondary public school in Qatar 

      Al-Wattary, Noor; Wyness, Michael ( Cogent OA , 2023 , Article)
      This paper is based on a study that explored the impact of a practitioner-designed social emotional program on students' wellbeing based on the results of the WEMWBS scale in a public secondary school in Qatar. This cluster ...

    • The Role of Demographic and Clinical Characteristics in Distinguishing Testicular Torsion from Torsion of the Appendix Testis: A Single-center Retrospective Study 

      Zvizdic, Zlatan; Aganovic, Amila; Milisic, Emir; Jonuzi, Asmir; Zvizdic, Denisa; ... more authors ( Karolinum - Nakladatelstvi Univerzity Karlovy , 2023 , Article)
      The acute scrotum (AS) in the pediatric population is a medical emergency. AS is usually caused by testicular torsion (TT) and torsion of the appendix testis (TAT). The current study explored which demographic and clinical ...

    • Thermogenic Modulation of Adipose Depots: A Perspective on Possible Therapeutic Intervention with Early Cardiorenal Complications of Metabolic Impairment 

      El-Yazbi, Ahmed F.; Elrewiny, Mohamed A.; Habib, Hosam M.; Eid, Ali H.; Elzahhar, Perihan A.; ... more authors ( American Society for Pharmacology and Experimental Therapy (ASPET) , 2023 , Article)
      Cardiovascular complications of diabetes and obesity remain a major cause for morbidity and mortality worldwide. Despite significant advances in the pharmacotherapy of metabolic disease, the available approaches do not ...

    • Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data 

      Alalawneh, Majdoleen; Rachid, Ousama; Abdallah, Ibtihal; Mahfouz, Ahmed; Elewa, Hazem; ... more authors ( Springer Science and Business Media Deutschland GmbH , 2023 , Article)
      Purpose To investigate real-world prescribing trends and clinical outcomes based on body mass index (BMI) categorization in patients who received rivaroxaban therapy. Methods This was a retrospective cohort study ...

    • The assessment of tumor-infiltrating lymphocytes in invasive apocrine carcinoma of the breast in relation to the HER2 status. 

      Gatalica, Zoran; Kuzmova, Nataliya; Rose, Inga; Ulamec, Monika; Peric Balja, Melita; ... more authors ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2023 , Article)
      In the current study, we assessed the prevalence and molecular features of HER2-low phenotype in the apocrine carcinomas of the breast (ApoCa) and its relationship with tumor-infiltrating lymphocytes (TILs). A cohort of ...