Medicine Research: Recent submissions
Now showing items 301-320 of 1820
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Small cell lung cancer associated small bowel obstruction, a diagnostic conundrum: A case report
( Wiley Online Library , 2024 , Article)Small cell lung cancer (SCLC), a neuroendocrine aggressive subtype of lung cancer, is associated with paraneoplastic disorders in about 9% of patients. In this report, we describe a middle-aged man who presented with chronic ... -
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
( Elsevier , 2024 , Article)BackgroundAs set out in Sustainable Development Goal 3.3, the target date for ending the HIV epidemic as a public health threat is 2030. Therefore, there is a crucial need to evaluate current epidemiological trends and ... -
The interplay between vitamin D status, subclinical inflammation, and prediabetes
( Elsevier , 2024 , Article)Vitamin D's role extends beyond classical calcium and phosphate homeostasis to encompass a pivotal influence on immune modulation and metabolic health. The mechanisms by which vitamin D exerts these effects involve its ... -
“Happily tired”: A descriptive qualitative study of the impact of the COVID-19 pandemic on women academics in Qatar
( Elsevier , 2024 , Article)The COVID-19 pandemic highlighted existing gender inequalities and inequities in academia, such as unequal workload distribution and insufficient recognition of women's scientific and institutional contributions. This study ... -
Human papillomavirus prevalence and genotypes in Gulf Cooperation Council countries: A scoping review 2017-2024
( HBKU Press , 2024 , Article)Background: Cervical cancer remains a global health challenge, claiming the lives of millions annually and having a significant impact on Gulf Cooperation Council (GCC) countries. Human papillomavirus (HPV), the primary ... -
Performance Characteristics of Next-Generation Sequencing–Based Engraftment Monitoring and Microchimerism Detection in Allogeneic Hematopoietic Cell Transplantation A Practical Approach for Clinical Assay Validation
( Elsevier , 2024 , Article)Chimerism analysis by next-generation sequencing (NGS) is an emerging method for engraftment monitoring after allogeneic hematopoietic cell transplantation. A high-sensitivity method is required for the detection of ... -
Etiology of exudative pleural effusion among adults: differentiating between tuberculous and other causes, a multicenter prospective cohort study
( Elsevier , 2024 , Article)ObjectivesExudative pleural effusions have a broad etiology and usually necessitate further investigative workup, including invasive procedures. This study aimed to evaluate and compare the demographic, clinical, and ... -
Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury
( Elsevier , 2024 , Article)Traumatic brain injury (TBI) and lifestyle habits such as Western diet (WD) consumption represent two risk factors that affect an individual's health outcome globally. Individuals with TBI have a greater risk of mortality ... -
Generation of Novel Tumour-Selective SEA Superantigen-Based Peptides with Improved Safety and Efficacy for Precision Cancer Immunotherapy
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Bacterial superantigens are T-cell-stimulatory protein molecules which produce massive cytokines and cause human diseases. Due to their ability to activate up to 20% of resting T-cells, they have effectively killed ... -
Postmicturition dribble in men with no previous urogenital surgery: Systematic review and meta-analysis of treatment modalities
( John Wiley & Sons , 2023 , Article)Introduction: Postmicturition dribble (PMD) is common in males. Little is known about PMD etiology, but it is either secondary to urethral/prostatic surgery or primary (no previous surgery). Despite PMD's high prevalence, ... -
Tubulocystic renal cell carcinoma: A case report of rare tumor
( Elsevier Ltd , 2024 , Article)Tubulocystic renal cell carcinoma (RCC) is a rare renal cancer first recognized by the WHO in 2016 as independent disease category, characterized by its typically indolent features and low rates of metastasis. We present ... -
Automated grading of prenatal hydronephrosis severity from segmented kidney ultrasounds using deep learning
( Elsevier , 2024 , Article)Background and motivations: Antenatal or prenatal hydronephrosis (AHN) is a common kidney complication in unborn children. While AHN is generally benign and resolves over time, this condition can inflict serious kidney ... -
Targeting of S-phase kinase associated protein 2 stabilized tumor suppressors leading to apoptotic cell death in squamous skin cancer cells
( Elsevier , 2024 , Article)S-phase kinase-associated protein 2 (Skp2) is an F-box protein overexpressed in human cancers and linked with poor prognosis. It triggers cancer pathogenesis, including stemness and drug resistance. In this study, we have ... -
Report from the World Health Organization's immunization and vaccines-related implementation research advisory committee (IVIR-AC) ad hoc meeting, 28 June - 1 July 2024
( Elsevier , 2024 , Conference)The World Health Organization's Immunization and Vaccines-related Implementation Research Advisory Committee (IVIR-AC) serves to independently review and evaluate vaccine-related research to maximize the potential impact ... -
National study comparing psychiatric presentations among migrants and citizens in Qatar
( Elsevier , 2024 , Article)Arab countries host 10 % of the global migrant population, yet research on the mental health of migrant workers within this region is notably lacking. Addressing this gap, our study marks the inaugural nationwide investigation ... -
Alterations in Choline Metabolism in Non-Obese Individuals with Insulin Resistance and Type 2 Diabetes Mellitus
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)The prevalence of non-obese individuals with insulin resistance (IR) and type 2 diabetes (T2D) is increasing worldwide. This study investigates the metabolic signature of phospholipid-associated metabolites in non-obese ... -
Unique Lessons From the Natural Progression of Rejection in Human Uterine Allografts
( John Wiley and Sons Inc , 2024 , Article)Introduction: Uterus transplantation (UTx) is a novel treatment for absolute uterine infertility. Acute T cell-mediated rejection (TCMR) can be monitored only through serial cervical biopsies. Methods: This study, the first ... -
Commentary to "Comparison of hypospadias phenotype pixel segmentation to GMS score"; towards precision care in hypospadias management: Navigating challenges and embracing innovation
( Elsevier , 2024 , Other)This article presents a comparison between hypospadias pixel segmentation and GMS score for the classification of hypospadias . Introducing a comprehensive and standardized approach to the assessment and surgical management ... -
Reply to letter to the editor: "Plate Objective Scoring Tool (POST) in distal hypospadias: Correlation with post-repair complications"
( Elsevier , 2024 , Article)We extend our sincere gratitude to the authors for their thoughtful and insightful letter concerning our article titled "Plate Objective Scoring Tool (POST) in distal hypospadias: Correlation with post-repair complications." ... -
Examining the perception of undergraduate health professional students of their learning environment, learning experience and professional identity development: a mixed-methods study
( BioMed Central Ltd , 2024 , Article)Background: The quality of the learning environment significantly impacts student engagement and professional identity formation in health professions education. Despite global recognition of its importance, research on ...
