Medicine Research: Recent submissions
Now showing items 661-680 of 1819
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An investigation into the avoidability of adverse drug reactions using the LAAT and modified Hallas tools
( Wolters Kluwer Health , 2020 , Article)An adverse drug reactions avoidability tool called the Liverpool ADR avoidability assessment tool (LAAT) was recently developed (for research purposes), and subsequently validated with mixed interrater reliability (IRR). ... -
An unusual case of modified Lemierre’s syndrome caused by staphylococcus aureus cellulitis
( International Scientific Literature Inc. , 2020 , Article)Patient: Male, 31-year-old Final Diagnosis: Lemierre’s Disease Symptoms: Conjunctival injection • eye pain and redness • fever • nasal swelling • periorbital oedema • ptosis • vesicular lesions nose Medication: — Clinical ... -
An investigation into the impact of enteric coated of aspirin in patients with newly diagnosed ischemic stroke (ECASIS)
( Wolters Kluwer Health , 2020 , Article)Introduction:Uncertainty remains regarding the impact of enteric-coated (EC) aspirin as it relates to the reduction of cardiovascular risk. We hypothesize that EC formulation based on a previous report may blunt aspirin ... -
Myxedema psychosis: A protocol for a systematic review and a pooled analysis
( Wolters Kluwer Health , 2020 , Article)Background: Myxedema psychosis (MP) is a rare presentation of hypothyroidism. Although known for >70 years, a significant lack of systematic literature describing this condition exists. This limits the clinician's ability ... -
Colchicine use might be associated with lower mortality in COVID-19 patients: A meta-analysis
( Wiley-Blackwell , 2021 , Article)Background: Colchicine was recently repurposed for the management of coronavirus disease 2019 (COVID-19). This rapid review and meta-analysis aimed to assess colchicine's impact on mortality outcomes in COVID-19 patients. ... -
The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS) study
( Springer Nature , 2022 , Article)Background and purpose: Uncertainty remains regarding the impact of enteric-coated aspirin (EC-ASA) on secondary prevention of ischemic stroke compared to plain aspirin (P-ASA). Hence, this study was designed to investigate ... -
An investigation into the avoidability of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome
( Springer Nature , 2021 , Article)Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rising morbidity amongst hospitalized patients. Whilst clinical protocols for the management of individual DRESS cases have been well established, ... -
Patch Testing as a Diagnostic Method for DRESS Syndrome That Brings Us Closer to a Certain Result: Letter to the Editor
( Esmon Publicidad S.A. , 2022 , Article)The recent clinical report by García-Paz et al [1] on a case of DRESS syndrome due to amoxicillin makes for interesting reading. In this report, a 26-year-old man presented with a rash whose clinical phenotype (according ... -
HCV cirrhotic patients treated with direct-acting antivirals: Detection of tubular dysfunction and resolution after viral clearance
( Wiley-Blackwell , 2021 , Article)Bilotti et al's1 recent excellent report on the prevalence of tubular and glomerular dysfunction in patients with HCV infection on direct-acting antiviral (DAA) agents, and their evolution following HCV clearance adds to ... -
Myxedema psychosis: Systematic review and pooled analysis
( Dove Medical Press , 2021 , Article)Background and Objective: The term myxedema psychosis (MP) was introduced to describe the occurrence of psychotic symptoms in patients with untreated hypothyroidism, but the optimal assessment and treatment of this condition ... -
SGLT-2 inhibitors associated euglycemic and hyperglycemic DKA in a multicentric cohort
( Springer Nature , 2021 , Article)Euglycemic diabetic ketoacidosis (EuDKA) secondary to Sodium-glucose co-transporter-2 inhibitors (SGLT2i) in type 2 diabetes mellitus (T2D) is a rare but increasingly reported phenomenon. Not much is known about the burden ... -
Polypharmacy and drug interactions amongst cirrhotic patients discharged from a tertiary center: Results from a national quality improvement audit
( Elsevier , 2020 , Article)Background and Study AimsAuditing of polypharmacy is particularly essential in patients with cirrhosis because of the crucial role of liver in drug metabolism. The aim of this study was to audit the drug prescribed in this ... -
QTc evaluation in COVID-19 patients treated with chloroquine/hydroxychloroquine: A letter to the editor
( Wiley-Blackwell , 2020 , Article)We read with interest Monzani et al's report1 on QT pro-longation in COVID-19 patients on treatment with chloro-quine/hydroxychloroquine (CQ/HCQ). Her report highlights the therapeutic morbidities ... -
Does colchicine reduce mortality in patients with COVID-19 clinical syndrome? An umbrella review of published meta-analyses
( Elsevier , 2023 , Article)BackgroundDespite significant improvements in both treatment and prevention strategies, as well as multiple commissioned reviews, there remains uncertainty regarding the survival benefit of repurposed drugs such as colchicine ... -
Clinical, Radiological, and Outcome Characteristics of Acute Pulmonary Embolism: A 5-year Experience from an Academic Tertiary Center
( HBKU Press , 2022 , Article)Background: Acute pulmonary embolism (PE) is a common and potentially life-threatening condition. This comprehensive study from a Gulf Cooperation Council (GCC) country aimed to evaluate the clinical, radiological, and ... -
Commentary: Potentially inappropriate medication among older patients with diabetic kidney disease
( Frontiers Media SA , 2023 , Article)Wang et al. (2020)’s recent report on the burden and morbidity consequences of potentially inappropriate medications (PIMs) in a select cohort of type 2 diabetic mellitus (T2DM) patients was both instructive and an “inflection ... -
The effect of low-dose aspirin on platelet function during pregnancy compared to placebo: An explorative study. A letter to the Editor
( Elsevier , 2022 , Article)We read with interest Bij de Weg et al.’s, recent mechanistic report on the inhibitory effect of Aspirin on platelet function in patients with pre-eclampsia [1]. Compared to placebo, this study found that 80 mg of generic ... -
Seroconversion and safety of Covid-19 vaccines in patients with chronic liver disease and liver transplant: A systematic review
( HBKU Press , 2023 , Article)Background and Aims: As part of the COVID-19 control strategy, a growing number of vaccine portfolios evolved and got fast-tracked through regulatory agencies, with a limited examination of their efficacy and safety in ... -
Colchicine and mortality outcomes in patients with coronavirus disease (COVID-19)
( Elsevier , 2023 , Article)One of the therapeutic hallmarks of the ongoing (COVID-19) pandemic has been the different iterations of successful and sometimes unsuccessful attempts at re-purposing of drugs with pre-existing market authorization for ... -
Association of polypharmacy with incidence of CKD: a retrospective cohort study: a letter to the Editor
( Springer Nature , 2023 , Article)Kimura et al.’s recently published report on a retrospective examination of the Fukushima chronic kidney disease (CKD) patient cohort provides an interesting perspective on this rising therapeutic morbidity [1]. The study ...
