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Can commercial automated immunoassays be utilized to predict neutralizing antibodies after SARS-CoV-2 infection? A comparative study between three different assays.
(
IMR
, 2021 , Article)
Background: High-throughput assays that can infer neutralizing activity against SARS-CoV-2 are of great importance for assessing the immunity induced by natural infection and COVID-19 vaccines. We aimed to evaluate the ...
Loop-mediated isothermal amplification (Lamp): A rapid, sensitive, specific, and cost-effective point-of-care test for coronaviruses in the context of covid-19 pandemic
(
MDPI
, 2020 , Article)
The rampant spread of COVID-19 and the worldwide prevalence of infected cases demand a rapid, simple, and cost-effective Point of Care Test (PoCT) for the accurate diagnosis of this pandemic. The most common molecular tests ...
The prevalence of adaptive immunity to COVID-19 and reinfection after recovery - a comprehensive systematic review and meta-analysis.
(
Taylor & Francis
, 2022 , Article)
This study aims to estimate the prevalence and longevity of detectable SARS-CoV-2 antibodies and T and B memory cells after recovery. In addition, the prevalence of COVID-19 reinfection and the preventive efficacy of ...
Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar’s experience
(
International Society of Global Health
, 2022 , Article)
Background: The effective reproduction number, Rt, is a tool to track and understand epidemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset ...
Antiviral activity of glucose-derived reactive metabolite, methylglyoxal against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
(
Hamad bin Khalifa University Press (HBKU Press)
, 2022 , Article)
Background: The ongoing coronavirus disease 2019 (COVID-19) pandemic has resulted in a global health emergency. With incomplete vaccination and incomplete protection of the vaccinated population, there remains an urgent ...
Modeling the population-level impact of treatment on COVID-19 disease and SARS-CoV-2 transmission
(
Elsevier
, 2022 , Article)
Different COVID-19 treatment candidates are under development, and some are becoming available including two promising drugs from Merck and Pfizer. This study provides conceptual frameworks for the effects of three types ...
Immunomodulatory and Anti-Inflammatory Effects of Berberine in Lung Tissue and its Potential Application in Prophylaxis and Treatment of COVID-19
(
IMR Press
, 2022 , Article Review)
Natural products with known safety profiles are a promising source for the discovery of new drug leads. Berberine presents an example of one such phytochemical that has been extensively studied for its anti-inflammatory ...
Periodontitis and coronavirus disease 2019
(
Wiley
, 2022 , Article Review)
The coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 is usually a mild condition; however, in some cases it can result in severe sickness and even death. Thus, understanding the reasons ...
SARS-CoV-2 does not replicate in HaCaT spontaneously immortalized human keratinocytes: implications for the pathogenesis of COVID-19-associated skin manifestations
(
John Libbey Eurotext
, 2022 , Article)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-related cutaneous manifestations have been reported [1], however, the direct or indirect role of SARS-CoV-2 infection in their pathophysiology is still debated ...
COVID-19 and male infertility: An overview of the disease
(
Lippincott, Williams & Wilkins
, 2022 , Article)
Since SARS-CoV-2 infection was first discovered in December 2019 in Wuhan City in China, it spread rapidly and a global pandemic of COVID-19 has occurred. According to several recent studies on SARS-CoV-2, the virus primarily ...