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Now showing items 11-20 of 23
Yttrium oxide nanoparticle loaded scaffolds with enhanced cell adhesion and vascularization for tissue engineering applications
(
Elsevier Ltd
, 2019 , Article)
In situ tissue engineering is emerging as a novel approach in tissue engineering to repair damaged tissues by boosting the natural ability of the body to heal itself. This can be achieved by providing suitable signals and ...
Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo
(
Elsevier B.V.
, 2019 , Article)
In this study, we formulated silymarin-HSA nanoplex and assayed its ability to reduce LPS-induced toxicity in vitro and in vivo. Silymarin molecules were encapsulated into HSA nanoplex and the loading efficiency and ...
Designing and performance evaluation of polyelectrolyte multilayered composite smart coatings
(
Elsevier B.V.
, 2019 , Article)
This work reports the synthesis of polyelectrolyte microcapsules and its effect on the anti-corrosion performance of polymeric coating applied on steel substrates. In situ polymerization technique was used for the synthesis ...
Plasmonic gold nanoparticles: Optical manipulation, imaging, drug delivery and therapy
(
Elsevier B.V.
, 2019 , Article Review)
Over the past two decades, the development of plasmonic nanoparticle (NPs), especially gold (Au) NPs, is being pursued more seriously in the medical fields such as imaging, drug delivery, and theranostic systems. However, ...
Silver nanoparticle impregnated chitosan-PEG hydrogel enhances wound healing in diabetes induced rabbits
(
Elsevier B.V.
, 2019 , Article)
Non-healing wounds are among the serious complications of type-2-diabetes around the globe, associated with high incidence of bacterial infection, chronic nerve and blood vessel damage, and eventually repeated amputation ...
Albumin binding, antioxidant and antibacterial effects of cerium oxide nanoparticles
(
Elsevier B.V.
, 2019 , Article)
Herein, the interaction of CeO2 NPs with HSA was explored by fluorescence, CD, UV–vis and molecular docking studies. Afterwards, the antioxidant activity of CeO2 NPs against H2O2-induced oxidative stress in BM-MSCs were ...
The effect of aluminum oxide on red blood cell integrity and hemoglobin structure at nanoscale
(
Elsevier B.V.
, 2019 , Article)
Herein, we explored the interaction of Al2O3 NPs with RBCs and Hb to determine the effect of Al2O3 NPs on hemolytic activity and Hb denaturation. The percentage of hemolysis of extracts and direct contact assays triggered ...
Nitric oxide releasing chitosan-poly (vinyl alcohol) hydrogel promotes angiogenesis in chick embryo model
(
Elsevier B.V.
, 2019 , Article)
The lack of angiogenic activity is one of the serious complications of chronic wounds associated with delayed wound closure, chronic ulceration, and subsequent limb amputation. Multiple lines of evidence suggest that nitric ...
Kidney-on-a-chip: untapped opportunities
(
Elsevier B.V.
, 2018 , Article Review)
The organs-on-a-chip technology has shown strong promise in mimicking the complexity of native tissues in vitro and ex vivo, and recently significant advances have been made in applying this technology to studies of the ...
In vitro models and systems for evaluating the dynamics of drug delivery to the healthy and diseased brain
(
Elsevier B.V.
, 2018 , Article Review)
The blood-brain barrier (BBB) plays a crucial role in maintaining brain homeostasis and transport of drugs to the brain. The conventional animal and Transwell BBB models along with emerging microfluidic-based BBB-on-chip ...