تصفح Pharmacy Research حسب العنوان
السجلات المعروضة 1084 -- 1103 من 1231
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Strategies to Optimize Dual Antiplatelet Therapy after Coronary Artery Stenting in Acute Coronary Syndrome
( SAGE Publications Ltd , 2017 , Article)The use of aspirin and a P2Y12 receptor antagonist as dual antiplatelet therapy (DAPT) has become the treatment of choice in patients with acute coronary syndrome (ACS) and percutaneous coronary intervention to prevent ... -
Structure-activity relationship investigation of methoxy substitution on anticancer pyrimido[4,5-c]quinolin-1(2H)-ones
(2013 , Article)Pyrimido[4,5-c]quinolin-1(2H)-one derivatives were shown to exert interesting biological activities including anticancer, antimicrobial, and cardiovascular. Substitution with methoxy groups played a crucial role in the ... -
Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes
( Frontiers Media SA , 2024 , Article)Introduction: Diabetes mellitus (DM) is recognized as one of the oldest chronic diseases and has become a significant public health issue, necessitating innovative therapeutic strategies to enhance patient outcomes. ... -
Structured Multi-Skill Assessment (SMSA) in pharmacy: A contextual adaptation for authentic assessment for colleges of pharmacy and beyond
( Bloomsbury Qatar Foundation Journals , 2015 , Article)There is a need for a contextual adaptation model of the Objective Structured Clinical Examination (OSCE) procedures and assessment methods into diverse contexts with great cultural diversity that is both affordable and ... -
Structure–activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro
( Springer Netherlands , 2017 , Article)Endoplasmic reticulum (ER) is the key organelle involved in protein folding and maturation. Emerging studies implicate the role of ER stress in the development of chronic kidney disease. Thus, there is an urgent need for ... -
Student and graduate perceptions regarding Canadian-based accreditation of a pharmacy program in Qatar
( American Association of Colleges of Pharmacy , 2019 , Article)Objective. To determine student and alumni perceptions of a Canadian-based pharmacy degree accreditation in a Middle Eastern setting and to explore the impact on patient care practices. Methods. Current and former Doctor ... -
Student and pre-registration pharmacist performance in a UK Prescribing Assessment
( Springer Nature , 2021 , Article)Student and pre-registration pharmacist performance in a UK Prescribing Assessment’: room for improvement and need for curricular change Background Increasingly the global policy direction is for patient-facing pharmacist ... -
Students' conception of local responses to global problems for a more peaceful and sustainable world: A collaborative education project between Brazil, Canada, Qatar, and New Zealand
( Wiley , 2022 , Article)Background: The concept of global citizenship aims to prepare learners to be able to function and be competitive within a global environment. Successful learners may effectively “think globally” but “act locally,” aiming ... -
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Spliceosome
( Frontiers Media S.A. , 2021 , Article)Background: Tumor glycolysis is a target for cancer chemotherapy. Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase ... -
Studies of the precipitation pattern of paclitaxel in intravenous infusions and rat plasma using laser nephelometry
( Taylor and Francis Ltd , 2018 , Article)Cremophor EL (CrEL) is commonly used to solubilize paclitaxel (Ptx); a widely established anticancer agent used against many types of cancer. Using laser-based microplate nephelometry, in this work we assessed the precipitation ... -
Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan
( Elsevier , 2023 , Article)Colon cancer (CRC) is the second leading cause of death and the third most diagnosed cancer worldwide. Although curcumin (CUR) has demonstrated a potent anticancer activity, it is characterized by its poor solubility, low ... -
A study to investigate the implementation process and fidelity of a hospital to community pharmacy transfer of care intervention.
( Public Library of Science , 2021 , Article)Hospital to community pharmacy transfer of care medicines-related interventions for inpatients discharged home aim to improve continuity of care and patient outcomes. One such intervention has been provided for seven years ... -
Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
( Elsevier , 2021 , Article)HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. It is characterized by aggressive behavior and treatment resistance. On the other hand, poly (amidoamine) (PAMAM) ... -
Sugar-based novel niosomal nanocarrier system for enhanced oral bioavailability of levofloxacin
( Taylor and Francis Ltd , 2016 , Article)Context: Vesicular systems have attracted great attention in drug delivery because of their amphiphilicity, biodegradability, non-toxicity and potential for increasing drug bioavailability. Objective: A novel sugar-based ... -
Suicide literacy mediates the path from religiosity to suicide stigma among Muslim community adults: Cross-sectional data from four Arab countries.
( SAGE , 2023 , Article)The majority of research attention has been devoted to the link between religiosity and suicide risk, and a considerable amount of studies has been carried out on how stigma impacts individuals with mental health problems ... -
Suitability of digoxin as a P-glycoprotein probe: Implications of other transporters on sensitivity and specificity
( John Wiley & Sons Ltd. , 2014 , Article)The study of transporter-mediated drug–drug interactions (DDI) requires use of appropriate probes to reflect transporter function. Digoxin is often used as a probe in DDI studies involving P-glycoprotein (P-gp) and is ... -
Summative assessment in a doctor of pharmacy program: a critical insight
( Dove Press , 2015 , Article)Background: The Canadian-accredited post-baccalaureate Doctor of Pharmacy program at Qatar University trains pharmacists to deliver advanced patient care. Emphasis on acquisition and development of the necessary knowledge, ... -
Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
( Elsevier , 2020 , Article)© 2020 Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important ... -
Surfactant therapy for meconium aspiration syndrome in neonates: A systematic overview of systematic reviews and recent clinical trials
( Becaris Publishing Ltd , 2020 , Article)Aim: To conduct a systematic overview of systematic reviews (SRs) and randomized clinical trials (RCTs) on surfactant therapy in neonatal meconium aspiration syndrome. Methods: We searched EMBASE, PROQUEST and PubMed to ... -
Survey Among Healthcare Professionals On The Implications Of Pharmacogenetics And Its Limitations
( Hamad bin Khalifa University Press (HBKU Press) , 2014 , Conference Paper)Pharmacists are expected to play an important role in applying pharmacogenetic discoveries to patient care. Despite the increased attention to genetic research in Qatar, clinicians' attitude towards pharmacogenetics' ...
