Browsing Pharmacy Research by Title

Now showing items 539-558 of 1227

    • Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study 

      Perera, Minoli A; Cavallari, Larisa H; Limdi, Nita A; Gamazon, Eric R; Konkashbaev, Anuar; ... more authors ( Elsevier , 2013 , Article)
      Summary BackgroundVKORC1 and CYP2C9 are important contributors to warfarin dose variability, but explain less variability for individuals of African descent than for those of European or Asian descent. We aimed to identify ...

    • Genomewide association analysis of warfarin dose requirements in Middle Eastern and North African populations 

      El Rouby, Nihal; Shahin, Mohamed H.; Bader, Loulia; Khalifa, Sherief I.; Elewa, Hazem ( Wiley-Blackwell , 2022 , Article)
      To date, there has been no genomewide association study (GWAS) from the Middle East and North African (MENA) region to identify genetic variants associated with warfarin dose variability using this approach. In this study, ...

    • Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects 

      Alsaad A.M.; Al-Arifi M.N.; Maayah Z.H.; Attafi I.M.; Alanazi F.E.; ... more authors ( Taylor and Francis Ltd , 2019 , Article)
      Although a plethora of studies have examined tobacco smoke-cancer disease association, the involvement of cellular genetic toxicity remains unclear. Therefore, the present study provides molecular evidence for a pathway ...

    • Geriatric education in schools of pharmacy: Students' and educators' perspectives in Qatar and Canada 

      Zolezzi M.; Sadowski C.A.; Al-Hasan N.; Gad Alla O. ( Elsevier Inc. , 2018 , Article)
      Introduction: Older adults constitute the largest population admitted to hospitals due to chronic diseases, which requires appropriate prescribing of medications and comprehensive pharmaceutical care. The views and ...

    • Global comparison of professional positioning by pharmacy programs towards prospective students 

      Wilby, Kyle John; Rainkie, Daniel C. ( Elsevier , 2020 , Article)
      © 2020 Elsevier Inc. Background: Enrolment of capable prospective students for pharmacy programs is a major priority for the profession. The way in which these students perceive a future career in pharmacy may be dependent ...

    • Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries 

      Pathadka, Swathi; Yan, Vincent K.C.; Neoh, Chin Fen; Al-Badriyeh, Daoud; Kong, David C.M.; ... more authors ( Springer , 2022 , Article)
      Background: Understanding the trend of global antifungal agent consumption could assist with identification of global healthcare policy inadequacies and promote accessibility and availability of antifungal agents. Methods: ...

    • Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 

      Kanyin Liane, Ong; Stafford, Lauryn K; McLaughlin, Susan A; Boyko, Edward J; Vollset, Stein Emil; ... more authors ( Elsevier , 2023 , Article)
      BackgroundDiabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global ...

    • Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime 

      Imran, Muhammad; Shah, Muhammad Raza; Ullah, Farhat; Ullah, Shafi; Elhissi, Abdelbary M. A.; ... more authors ( Elsevier B.V. , 2016 , Article)
      This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant synthesized and characterized in our laboratory for increased oral bioavailability of Cefixime. The surfactant was synthesized by simple ...

    • Gold-containing compound BDG-I inhibits the growth of A549 lung cancer cells through the deregulation of miRNA expression 

      Alhoshani A.; Alrashdi A.; Alhosaini K.; Alanazi F.E.; Alajez N.M.; ... more authors ( Elsevier B.V. , 2018 , Article)
      Gold complex bis(diethyldithiocarbamato-gold(I)) bis(diphenylphosphino) methane (BDG-I) is cytotoxic toward different cancer cell lines. We compared the cytotoxic effect of BDG-I with that of cisplatin in the A549 lung ...

    • Greensporone A, a fungal secondary metabolite suppressed constitutively activated AKT via ROS generation and induced apoptosis in leukemic cell lines 

      Prabhu K.S.; Siveen K.S.; Kuttikrishnan S.; Jochebeth A.; Ali T.A.; ... more authors ( MDPI AG , 2019 , Article)
      Greensporone A is a fungal secondary metabolite that has exhibited potential in vitro for anti-proliferative activity in vitro. We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. ...

    • Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines 

      Prabhu K.S.; Siveen K.S.; Kuttikrishnan S.; Iskandarani A.N.; Khan A.Q.; ... more authors ( Frontiers Media S.A. , 2018 , Article)
      Therapeutic agents used in the treatment of cancer are known to develop resistance against cancer cells. Hence, there is a continuing need to investigate novel agents for the treatment and management of cancer. Antitumor ...

    • Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway 

      Akhtar, Sabah; Zarif, Lubna; Kuttikrishnan, Shilpa; Prabhu, Kirti S.; Patil, Kalyani; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)
      Multiple myeloma (MM) is a hematological disorder characterized by the abnormal expansion of plasma cells in the bone marrow. Despite great advances over the past three decades in discovering the efficacious therapies for ...

    • Guiding Factors and Surface Modification Strategies for Biomaterials in Pharmaceutical Product Development 

      Maheshwari, Neha; Kumar Atneriya, Umesh; Tekade, Muktika; Sharma, Mukesh Chandra; Elhissi, Abdelbary; ... more authors ( Elsevier , 2019 , Book chapter)
      With the technological advent in the field of drug delivery and medicines, biomaterials become important owing to their properties such as biocompatibility, functionality, and bioactive and bioinert nature. However, the ...

    • Haematococcus pluvialis Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells 

      Alateyah, Nouralhuda; Ahmad, Salma M. S.; Gupta, Ishita; Fouzat, Arij; Thaher, Mahmoud Ibrahim; ... more authors ( Frontiers Media S.A. , 2022 , Article)
      Breast cancer (BC) is the most common malignant cancer in females worldwide. Drug resistance, toxicity, and the failure of current therapies to completely cure BC has challenged conventional medicine. Consequently, ...

    • Has low-dose intracoronary thrombolysis gained ground in primary percutaneous intervention? 

      Kaddoura, Rasha; Mohamed Ibrahim, Mohamed Izham; Arabi, Abdul Rahman ( SAGE , 2022 , Article)
      Reducing thrombus burden would improve patient’s outcomes. Low-dose intracoronary thrombolytic agent administration has been considered to improve myocardial microcirculation, cardiac function, and major adverse cardiovascular ...

    • Health priorities of the Nepal Government: where are the essential medicines? 

      Bhuvan, K.C.; Poudel, Arjun; Mohamed Ibrahim, Mohamed Izham B. ( Blackwell Publishing Ltd , 2012 , Article)

    • Health priorities of the Nepal Government: Where are the essential medicines? 

      Bhuvan, K.C.; Poudel, A.; Ibrahim, Mohamed Izham MohamedB. ( Blackwell Publishing Ltd , 2012 , Article)
      [No abstract available]

    • Health related quality of life assessment in acute coronary syndrome patients: The effectiveness of early phase I cardiac rehabilitation 

      Anchah, Lawrence; Hassali, Mohamed Azmi; Lim, Melissa Siaw Han; Ibrahim, Mohamed Izham Mohamed; Sim, Kui Hian; ... more authors ( BioMed Central Ltd. , 2017 , Article)
      Background: Acute Coronary Syndrome (ACS) is one of the most burdensome cardiovascular diseases in terms of the cost of interventions. The Cardiac Rehabilitation Programme (CRP) is well-established in improving clinical ...

    • Health sciences students' and instructors' perceptions of the emergency switch to virtual internship amid the COVID-19 pandemic: A case from Qatar 

      Bawadi, Hiba; Abdul Rahim, Hanan; Moawad, Joyce; Shami, Rula; Du, Xiangyun; ... more authors ( Frontiers Media , 2022 , Article)
      In efforts to contain the COVID-19 pandemic, health colleges at Qatar University shifted their clinical training to virtual internships (VI) and project-based learning (PBL). The shift was new to students and faculty alike, ...

    • Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan 

      Ahmed, Ali; Saqlain, Muhammad; Bashir, Naila; Dujaili, Juman; Hashmi, Furqan; ... more authors ( Springer Science and Business Media Deutschland GmbH , 2021 , Article)
      Background: Health-related quality of life (HRQoL) is considered to be the fourth 90 of UNAIDS 90-90-90 target to monitor the effects of combination antiretroviral therapy (ART). ART has significantly increased the life ...