Browsing Pharmacy Research by Subject "letrozole"

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Preparation and Characterization of Letrozole-Loaded Poly (D,L-Lactide) Nanoparticles for Breast Cancer Therapy

Alemrayat, Bayan; Elhissi, Abdelbary; Younes, Husam ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference)
Introduction: Breast cancer has been ranked first as the most prevalent type of cancer and the leading cause of cancer-related mortality among women worldwide. Letrozole (LTZ), an aromatase inhibitor, has been shown to be ...
Preparation and characterization of letrozole-loaded poly(d,l-lactide) nanoparticles for drug delivery in breast cancer therapy

Alemrayat B.; Elhissi A.; Younes H.M. ( Taylor and Francis Ltd , 2019 , Article)
Letrozole (LTZ), an aromatase inhibitor used for the treatment of hormonally-positive breast cancer in postmenopausal women, has poor water solubility, rapid metabolism, and a range of side effects. In this study, polymer-based ...
Preparation and optimization of monodisperse polymeric microparticles using modified vibrating orifice aerosol generator for controlled delivery of letrozole in breast cancer therapy

Alemrayat B.; Elrayess M.A.; Alany R.G.; Elhissi A.; Younes H.M. ( Taylor and Francis Ltd. , 2018 , Article)
Letrozole (LTZ) is effective for the treatment of hormone-receptor-positive breast cancer in postmenopausal women. In this work, and for the first time, using vibrating orifice aerosol generator (VOAG) technology, monodisperse ...