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Clinical pharmacokinetic drug interactions associated with artemisinin derivatives and HIV-antivirals
(
Springer International Publishing
, 2014 , Article Review)
Management of HIV and malaria co-infection is challenging due to potential drug-drug interactions between antimalarial and HIV-antiviral drugs. Little is known of the clinical significance of these drug interactions, and ...
Evidence-Based Review of Pharmacotherapy Used for Parkinson's Disease Psychosis
(
SAGE Publications Inc.
, 2017 , Article Review)
Objective: To summarize and evaluate the existing literature regarding medications to treat Parkinson's disease (PD) psychosis. Data Sources: MEDLINE (1946 to March 2017), EMBASE (1980 to March 2017), CINAHL (1982 to March ...
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
(
Springer International Publishing
, 2017 , Article Review)
Background
Genetic polymorphisms are known to influence outcomes with phenytoin yet effects in the Middle East and North Africa region are poorly understood.
Objectives
The objective of this systematic review was to ...
A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
(
Springer International Publishing
, 2016 , Article Review)
Tuberculosis is a leading cause of infectious disease-related morbidity and mortality worldwide. Additionally, treatment is complex with most patients requiring combination therapy of first-line agents for multiple months. ...