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السجلات المعروضة 11 -- 14 من 14
Involvement of caveolae in hyperglycemia-induced changes in adiponectin and leptin expressions in vascular smooth muscle cells
(
Elsevier
, 2021 , Article)
Hyperglycemia exerts various harmful effects on the vasculature. Studies have shown an association between the levels of the adipokines leptin and adiponectin (APN) and vascular complications in diabetes mellitus. The aim ...
Myocardial proteases and cardiac remodeling
(
Wiley-Liss Inc.
, 2017 , Article Review)
Cardiac hypertrophy (CH), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. Despite the advances in cardiovascular research, there remains a need ...
Sestrin2 as a Protective Shield against Cardiovascular Disease
(
Multidisciplinary Digital Publishing Institute (MDPI)
, 2023 , Article)
A timely and adequate response to stress is inherently present in each cell and is important for maintaining the proper functioning of the cell in changing intracellular and extracellular environments. Disruptions in the ...
Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival
(
Spandidos publications
, 2021 , Article)
Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ...