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Now showing items 11-20 of 753
Reno-Protective Effects of Angiotensin Receptor Blockers in Hypertensive Rodent Models: A systematic review.
(
Qatar University Press
, 2021 , Poster)
Background and objective: Essential hypertension is a leading risk factor for chronic kidney disease, yet there is no conclusive evidence that lowering blood pressure alone improves renal outcome measures. Angiotensin-II ...
Advancing the Visibility, Impact, and Quality Metrics of Value in Health Regional Issues
(
Elsevier Inc.
, 2017 , Other)
[No abstract available]
CD56 expression in breast cancer induces sensitivity to natural killer-mediated cytotoxicity by enhancing the formation of cytotoxic immunological synapse
(
Nature Publishing Group
, 2019 , Article)
We examined the potential value of the natural killer (NK) cell line; NK-92, as immunotherapy tool for breast cancer (BC) treatment and searched for biomarker(s) of sensitivity to NK-92-mediated cytotoxicity. The cytotoxic ...
Administration error of benzathine penicillin G in a Saudi male
(
Wiley-Blackwell
, 2019 , Article)
Background
Benzathine penicillin G is indicated for intramuscular (IM ) administration. There have been reports of unintentional intravenous (IV ) administration, which has been associated with cardiorespiratory arrest ...
Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
(
Elsevier
, 2021 , Article)
Endoplasmic reticulum (ER) stress is an inflammatory response that contributes to endothelial dysfunction, a hallmark of cardiovascular diseases, in close interplay with oxidative stress. Recently, Sestrin2 (SESN2) emerged ...
Periprocedural Anticoagulation Management of Patients receiving Warfarin in Qatar: A Prospective Cohort Study
(
Elsevier
, 2021 , Article)
Background: The use of anticoagulant bridging remains controversial. This study was conducted to evaluate our warfarin periprocedural management in Qatar and investigate the associated clinical outcomes with such management. ...
Greensporone A, a fungal secondary metabolite suppressed constitutively activated AKT via ROS generation and induced apoptosis in leukemic cell lines
(
MDPI AG
, 2019 , Article)
Greensporone A is a fungal secondary metabolite that has exhibited potential in vitro for anti-proliferative activity in vitro. We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. ...
Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
(
NLM (Medline)
, 2018 , Article)
Cardiovascular diseases are the leading cause of death worldwide. One in three cases of heart failure is due to dilated cardiomyopathy. The Na+/H+ exchanger isoform 1 (NHE1), a multifunctional protein and the key pH regulator ...
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
(
Springer International Publishing
, 2017 , Article Review)
Background
Genetic polymorphisms are known to influence outcomes with phenytoin yet effects in the Middle East and North Africa region are poorly understood.
Objectives
The objective of this systematic review was to ...
Patient activation and patient-reported outcomes of men from a community pharmacy lifestyle intervention after prostate cancer treatment
(
Springer
, 2021 , Article)
Purpose: To report patient activation, which is the knowledge, skills, and confidence in self-managing health conditions, and patient-reported outcomes of men after prostate cancer treatment from a community pharmacy ...