Mechanical & Industrial Engineering: Recent submissions
Now showing items 701-720 of 1396
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Silybin as a potent inhibitor of a-synuclein aggregation and associated cytotoxicity against neuroblastoma cells induced by zinc oxide nanoparticles
( Elsevier B.V. , 2020 , Article)a-synuclein (a-syn) amyloid fibrils, the leading neurotoxic types, are predominately formed through interaction with nanoparticles (NPs). However, some natural compounds like silybin can reduce the formation of NPs-induced ... -
Electrospun chitosan membranes containing bioactive and therapeutic agents for enhanced wound healing
( Elsevier B.V. , 2020 , Article)Electrospinning is one of the most promising techniques for generating porous, nonwoven, and submicron fiber-based membranes for various applications such as catalysis, sensing, tissue engineering and wound healing. Wide ... -
Carboxymethylcellulose hybrid nanodispersions for edible coatings with potential anti-cancer properties
( Elsevier B.V. , 2020 , Article)Curcumin loaded lipid-polymer hybrid nanoparticles dispersions were fabricated from carboxymethylcellulose, stearic acid, polyethylene glycol and sesame oil using emulsion solvent evaporation method for their possible ... -
Advances of exosome isolation techniques in lung cancer
( Springer Science and Business Media B.V. , 2020 , Article)Lung cancer (LC) is among the leading causes of death all over the world and it is often diagnosed at advanced or metastatic stages. Exosomes, derived from circulating vesicles that are released from the multivesicular ... -
Development of point-of-care nanobiosensors for breast cancers diagnosis
( Elsevier B.V. , 2020 , Article)Nanobiosensors have played a key role as portable devices in the rapid breast cancer diagnosis and in clinical medicine like point-of-care devices. However, understanding biomarkers and nanomaterials is crucial for improving ... -
Application of gelatin nanoconjugates as potential internal stimuli-responsive platforms for cancer drug delivery
( Elsevier B.V. , 2020 , Article)Nanoparticles (NPs) have been continuously utilized for different implementations, most particularly for cancer drug delivery. A large number of NP-based drug delivery systems (DDSs) have been explored for cancer therapy ... -
Vascular cells proteome associated with bradykinin and leptin inflammation and oxidative stress signals
( MDPI , 2020 , Article)Among the primary contributors to cardiovascular diseases are inflammation and oxidative imbalance within the vessel walls as well as the fibrosis of rat aortic smooth muscle cell (RASMC). Bradykinin (BK) and leptin are ... -
Polymeric-based microneedle arrays as potential platforms in the development of drugs delivery systems
( Elsevier B.V. , 2020 , Article)Background: Microscopic patches as quite promising platforms in transdermal drug delivery suffer from conventional injections. In other hand, a wide range of pharmacokinetics, ranging from fast oral administration to ... -
Non-viral delivery systems of DNA into stem cells: Promising and multifarious actions for regenerative medicine
( Editions de Sante , 2020 , Article)Regenerative medicine has an exciting prospective to bring preventive and therapeutic benefits to a myriad of diseases. Different biological factors such as growth factors, therapeutic proteins, antibodies, plasmid DNA ... -
Cellular uptake and retention of nanoparticles: Insights on particle properties and interaction with cellular components
( Elsevier Ltd , 2020 , Article)The utilization of nanomaterials in the biological and medical field is quickly progressing, particularly in areas where traditional diagnostics and treatment approaches have limited success. The success of nanomaterials ... -
Stromal cell-derived factor loaded co-electrospun hydrophilic/hydrophobic bicomponent membranes for wound protection and healing
( Royal Society of Chemistry , 2020 , Article)Chronic wounds are one of the key concerns for people with diabetes, frequently leading to infections and non-healing ulcers, and finally resulting in the amputation of limbs/organs. Stromal cell-derived factor 1 (SDF1) ... -
NiFe2O4/poly(ethylene glycol)/lipid-polymer hybrid nanoparticles for anti-cancer drug delivery
( Royal Society of Chemistry , 2020 , Article)The present study reports the fabrication of hybrid nanoparticles consisting of nickel ferrite (NFO) for anti cancer drug delivery. The hybrid system was formulated from poly(vinyl alcohol)/stearic acid with PEG containing ... -
Natural halloysite nanotubes /chitosan based bio-nanocomposite for delivering norfloxacin, an anti-microbial agent in sustained release manner
( Elsevier B.V. , 2020 , Article)Applying nanotechnology to deliver drug could result in several benefits such as prolong duration of action, enhancement in overall bioavailability, targeting to specific site, low initial loading dose require, systemic ... -
Exploring the interaction of synthesized nickel oxide nanoparticles through hydrothermal method with hemoglobin and lymphocytes: Bio-thermodynamic and cellular studies
( Elsevier B.V. , 2020 , Article)The NiO NPs were synthesized by hydrothermal method and their interaction with Hb was investigated by employing fluorescence, UV?vis absorption techniques as well as docking studies. Also, the cytotoxic impacts of NiO NPs ... -
Gelatin-methacryloyl hydrogel based in vitro blood–brain barrier model for studying breast cancer-associated brain metastasis
( Taylor and Francis Ltd. , 2021 , Article)Breast cancer is one of the leading causes of brain metastasis. Metastasis to the brain occurs if cancer cells manage to traverse the ‘blood-brain barrier’ (BBB), which is a barrier with a very tight junction (TJ) of ... -
Growth factor loaded in situ photocrosslinkable poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/gelatin methacryloyl hybrid patch for diabetic wound healing
( Elsevier Ltd , 2021 , Article)Management of chronic diabetic ulcers remains as a major challenge in healthcare which requires extensive multidisciplinary approaches to ensure wound protection, management of excess wound exudates and promoting healing. ... -
Nanoporous iron oxide nanoparticle: hydrothermal fabrication, human serum albumin interaction and potential antibacterial effects
( Taylor and Francis Ltd. , 2021 , Article)Nanoporous iron oxide (Fe3O4) nanoparticles (NIONPs) have been widely used as promising agents in biomedical applications. Herein, the NIONPs were synthesized by one-step hydrothermal method and well-characterized by FESEM ... -
Hydrothermal method-based synthesized tin oxide nanoparticles: Albumin binding and antiproliferative activity against K562 cells
( Elsevier Ltd , 2021 , Article)The interaction of nanoparticles with protein and cells may provide important information regarding their biomedical implementations. Herein, after synthesis of tin oxide (SnO2) nanoparticles by hydrothermal method, their ... -
A review on the cleavage priming of the spike protein on coronavirus by angiotensin-converting enzyme-2 and furin
( Taylor and Francis Ltd. , 2021 , Article)The widespread antigenic changes lead to the emergence of a new type of coronavirus (CoV) called as severe acute respiratory syndrome (SARS)-CoV-2 that is immunologically different from the previous circulating species. ... -
Cerium Oxide Nanoparticle-Loaded Gelatin Methacryloyl Hydrogel Wound-Healing Patch with Free Radical Scavenging Activity
( American Chemical Society , 2021 , Article)Nonhealing wounds in diabetic patients are a critical challenge, which often cause amputation and mortality. High levels of oxidative stress and aberrations in antioxidant defense mechanisms increase the adverse manifestations ...
