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Now showing items 21-30 of 35
Deregulation of cell growth and apoptosis in UV-induced melanomagenesis
(
Frontiers in Bioscience
, 2020 , Article Review)
We have previously characterized the role of p16/Rb in coordinating the early events in UVB-irradiated skin. As an extension to this work, normal melanocytes and mutant p16-inducible melanoma cell models were employed to ...
PCF11, a Novel CD44-Downstream Transcriptional Target, Linking Its 3'-End Polyadenylation Function to Tumor Cell Metastasis
(
Frontiers Media S.A.
, 2022 , Article Review)
Breast Cancer (BC) is the most common and the major health issue in women worldwide. Metastasis, a multistep process, is the worst aspect of cancer and tumor cell invasion is the defining step. Tumor cell invasion requires ...
KYNU, a novel potential target that underpins CD44-promoted breast tumour cell invasion
(
Blackwell Publishing Inc.
, 2021 , Article Review)
Using a validated tetracycline-off-inducible CD44 expression system in mouse model, we have previously demonstrated that the hyaluronan (HA) receptor CD44 promotes breast cancer (BC) metastasis to the liver. To unravel the ...
The power of phytochemicals combination in cancer chemoprevention
(
Ivyspring International Publisher
, 2020 , Article Review)
Conventional therapies for cancer treatment have posed many challenges, including toxicity, multidrug resistance and economic expenses. In contrast, complementary alternative medicine (CAM), employing phytochemicals have ...
Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis
(
Elsevier Ltd
, 2022 , Article Review)
Antibody-dependent enhancement (ADE) has been associated with severe disease outcomes in several viral infections, including respiratory infections. In vitro and in vivo studies showed that antibody-response to SARS-CoV ...
Genetic engineering to enhance microalgal-based produced water treatment with emphasis on CRISPR/Cas9: A review
(
Frontiers Media
, 2023 , Article Review)
In recent years, the increased demand for and regional variability of available water resources, along with sustainable water supply planning, have driven interest in the reuse of produced water. Reusing produced water can ...
Nanomedicine as a Potential Tool against Monkeypox.
(
MDPI
, 2023 , Article Review)
Human monkeypox is a rare viral zoonosis that was first identified in 1970; since then, this infectious disease has been marked as endemic in central and western Africa. The disease has always been considered rare and ...
Photodegradation and Its Effect on Plant Litter Decomposition in Terrestrial Ecosystems: A Systematic Review
(
MDPI
, 2023 , Article Review)
Photodegradation is an important mechanism that affects carbon and nutrient cycling; a significant amount of data has been reported previously. The present review includes the effect of a wider spectrum of solar radiation ...
An overview of heavy metals toxicity in plants, tolerance mechanism, and alleviation through lysine-chelation with micro-nutrients—A novel approach
(
Springer
, 2022 , Article Review)
Abstract: Plants must adapt themselves to the prevailing conditions for their survival, resulting in the acquisition of a wide range of metal tolerance mechanisms. Although many metal elements are essential for the growth ...
Reuse of Sludge as Organic Soil Amendment: Insights into the Current Situation and Potential Challenges
(
MDPI
, 2023 , Article Review)
Sludge generation as an organic by-product of wastewater treatment has seen a consistent increase worldwide due to population growth and industrial activities. This poses a chronic challenge regarding management options ...