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The role of gene gjb2 and connexin 26 in hearing impairment
(
Palladin Institute of Biochemistry of the NASU
, 2018 , Article Review)
Gap Junction Beta 2 (GJB2) gene mutations are the leading causes of hereditary hearing impairment. This gene encodes various gap junction proteins such as connexin 26 (Cx26), which facilitate K+ homeostasis inside the ...
Phytochemical screening and assessment of pharmacological properties of Swertia chirayita (Roxb. ex fleming) root methanolic extract
(
Asian Network for Scientific Information
, 2017 , Article)
Background and Objective: Various parts of medicinal plants have been used to treat specific disorder from ancient times. Swertia chirayita (Roxb. ex Fleming) is a customary folklore medicine, used in the treatment of liver ...
Synergism between nigella sativa seeds extract and synthetic antibiotics against Mec A gene positive human strains of staphylococcus aureus
(
Asian Network for Scientific Information
, 2017 , Article)
Background and Objective: Synergistic combinations of various antimicrobial agents have been introduced as extra successful strategies to combat multidrug resistant (MDR) infections. This study was undertaken to evaluate ...
Recent advances in targeting protein arginine methyltransferase enzymes in cancer therapy
(
Taylor and Francis Ltd
, 2018 , Article Review)
Introduction: Exploration in the field of epigenetics has revealed the diverse roles of the protein arginine methyltransferase (PRMT) family of proteins in multiple disease states. These findings have led to the development ...
Anti-hypertensive Herbs and their Mechanisms of Action: Part I
(
Frontiers Media
, 2016 , Article)
The use of herbal therapies for treatment and management of cardiovascular diseases (CVDs) is increasing. Plants contain a bounty of phytochemicals that have proven to be protective by reducing the risk of various ailments ...
Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II
(
Frontiers Media
, 2016 , Article)
Traditional medicine has a history extending back to thousands of years, and during the intervening time, man has identified the healing properties of a very broad range of plants. Globally, the use of herbal therapies to ...
Rhus coriaria suppresses angiogenesis, metastasis and tumor growth of breast cancer through inhibition of STAT3, NFκB and nitric oxide pathways
(
Nature Publishing Group
, 2016 , Article)
Recently, we reported that Rhus coriaria exhibits anticancer activities by promoting cell cycle arrest and autophagic cell death of the metastatic triple negative MDA-MB-231 breast cancer cells. Here, we investigated the ...
Planning for assisted colonization of plants in a warming world
(
Nature Publishing Group
, 2016 , Article)
Assisted colonization is one way of facilitating range shifts for species that are restricted in their ability to move in response to climate change. Here we conceptualize and apply a new decision framework for modelling ...
Profile of Mental and Behavioral Disorders Among Preschoolers in a Tertiary Care Hospital in Oman: A Retrospective Study
(
Oman Medical Specialty Board
, 2016 , Article)
Objectives
Early diagnosis and prompt treatment of mental and behavioral disorders in preschoolers is critical for a better prognosis, ultimately leading to improved quality of life for both the child and the family. ...
Inflammogenesis of Secondary Spinal Cord Injury
(
Frontiers Media
, 2016 , Article)
Spinal cord injury (SCI) and spinal infarction lead to neurological complications and eventually to paraplegia or quadriplegia. These extremely debilitating conditions are major contributors to morbidity. Our understanding ...