Biological & Environmental Sciences: Recent submissions
Now showing items 301-320 of 938
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Ecosystem service supply and demand: Theory and management application
( ACTA ECOLOGICA SINICA , 2017 , Article)Ecosvstem service is a very important issue for current, sustainable scientific research. Environmental protection and management requirements are increasing and policymakers hope to incorporate ecological service information ... -
Toads in Qatar: The species present and their probable original source
( Elsevier , 2018 , Article)Toads are likely to have been introduced to Qatar, but little information is available on toad populations in the country, including the species present and their probable origin. Therefore, we collected tissue samples for ... -
The power of phytochemicals combination in cancer chemoprevention
( Ivyspring International Publisher , 2020 , Article Review)Conventional therapies for cancer treatment have posed many challenges, including toxicity, multidrug resistance and economic expenses. In contrast, complementary alternative medicine (CAM), employing phytochemicals have ... -
Nox2 activity is required in obesity-mediated alteration of bone remodeling
( Hindawi Limited , 2018 , Article)Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. Nox2 is one of the ... -
Deregulation of cell growth and apoptosis in UV-induced melanomagenesis
( Frontiers in Bioscience , 2020 , Article Review)We have previously characterized the role of p16/Rb in coordinating the early events in UVB-irradiated skin. As an extension to this work, normal melanocytes and mutant p16-inducible melanoma cell models were employed to ... -
KYNU, a novel potential target that underpins CD44-promoted breast tumour cell invasion
( Blackwell Publishing Inc. , 2021 , Article Review)Using a validated tetracycline-off-inducible CD44 expression system in mouse model, we have previously demonstrated that the hyaluronan (HA) receptor CD44 promotes breast cancer (BC) metastasis to the liver. To unravel the ... -
Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis
( Elsevier Ltd , 2022 , Article Review)Antibody-dependent enhancement (ADE) has been associated with severe disease outcomes in several viral infections, including respiratory infections. In vitro and in vivo studies showed that antibody-response to SARS-CoV ... -
PCF11, a Novel CD44-Downstream Transcriptional Target, Linking Its 3'-End Polyadenylation Function to Tumor Cell Metastasis
( Frontiers Media S.A. , 2022 , Article Review)Breast Cancer (BC) is the most common and the major health issue in women worldwide. Metastasis, a multistep process, is the worst aspect of cancer and tumor cell invasion is the defining step. Tumor cell invasion requires ... -
SIRT1, a novel transcriptional downstream target of CD44, linking its deacetylase activity to tumor cell invasion/metastasis
( Frontiers Media S.A. , 2022 , Article Review)Our tetracycline-off-inducible CD44 expression system previously established in mouse model, revealed that activation of CD44 with its major ligand hyaluronan (HA) promoted breast cancer (BC) metastasis to the liver. To ... -
Vitamin D receptor gene polymorphisms influence on clinical profile and bone mineral density at different skeletal sites in postmenopausal osteoporotic women.
( Wiley , 2023 , Article)Bone remodeling is marked by bone synthesis and absorption balance, and any altered dynamic in this process leads to osteoporosis (OP). The interaction of hormonal, environmental and genetic factors regulate bone metabolism. ... -
Towards Gas Hydrate-Free Pipelines: A Comprehensive Review of Gas Hydrate Inhibition Techniques
( MDPI , 2022 , Article Review)Gas hydrate blockage is a major issue that the production and transportation processes in the oil/gas industry faces. The formation of gas hydrates in pipelines results in significant financial losses and serious safety ... -
Autoinflammation in Syndromic Hidradenitis Suppurativa: The Role of AIM2.
( MDPI , 2023 , Report)AIM2 is a key cytoplasmatic pathogen-sensor that detects foreign DNA from viruses and bacteria; it can also recognize damaged or anomalous presence of DNA, promoting inflammasome assembly and activation with the secretion ... -
Free vibration of FG-GPLRC conical panel on elastic foundation
( Techno-Press , 2020 , Article)Present research is aimed to investigate the free vibration behavior of functionally graded (FG) nanocomposite conical panel reinforced by graphene platelets (GPLs) on the elastic foundation. Winkler-Pasternak elastic ... -
Haematococcus pluvialis Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells
( Frontiers Media S.A. , 2022 , Article)Breast cancer (BC) is the most common malignant cancer in females worldwide. Drug resistance, toxicity, and the failure of current therapies to completely cure BC has challenged conventional medicine. Consequently, ... -
Insights into the degradation mechanism of PET and PP under marine conditions using FTIR
( Elsevier , 2023 , Article)Plastics possess diverse functional properties that have made them extremely desirable. However, due to poor waste management practices, large quantities eventually end up in the oceans where their degradation begins. ... -
Effect of near-infrared and blue laser light on vero E6 cells SARS-CoV-2 infection model
( Wiley , 2022 , Article)Photobiomodulation therapy (PBMT) employing laser light has been emerging as a safe strategy to challenge viruses. In this study the effect of blue and near-infrared (NIR) laser light was assessed in an in vitro model of ... -
Realizing algae value chains in arid environments: an Arabian Peninsula perspective
( Elsevier , 2022 , Article)Algae are a promising feedstock for the sustainable production of feed, fuels, and chemicals. Especially in arid regions such as the Arabian Peninsula, algae could play a significant role in enhancing food security, economic ... -
Mapping of aeolian deposits of an industrial site in the arid region using the TIR bands of ASTER and study of physicochemical characters and stabilization of sand erosion
( Taylor and Francis Group , 2022 , Article)This study describes the spectral emissive character of silicate and carbonate minerals of aeolian deposits and maps the deposits and sand encroachments that occurred in and around the site 5/6 of Qatar Fertilizer Company ... -
Can Polymorphisms in NLRP3 Inflammasome Complex Be Associated with Postmenopausal Osteoporosis Severity?
( MDPI , 2022 , Article)The immune system plays a critical role in bone homeostasis and, consequently, in the pathophysiology of postmenopausal osteoporosis (OP) since estrogen deficiency induces the inflammasome and increases production of ... -
A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis
( Frontiers Media , 2022 , Article)Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with a multifactorial aetiology that involves a strict interplay between genetic factors, immune dysregulation and lifestyle. Familial forms represent ...
