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AuthorAl-Ruweidi, Mahmoud Khatib A.A.
AuthorKhater, Nada
AuthorAlkaabi, Haya Rashid
AuthorHasan, Maram
AuthorYalcin, Huseyin C.
Available date2022-12-29T05:10:30Z
Publication Date2022
Publication NameImmunology of the GI Tract - Recent Advances
Identifierhttp://dx.doi.org/10.5772/intechopen.106184
CitationAl-Ruweidi, M. K. A. , Khater, N., Alkaabi, H. R. , Hasan, M., & Yalcin, H. C. (2022). Autoimmune Diseases of the GI Tract Part I: Etiology and Pathophysiology. In (Ed.), Immunology of the GI Tract - Recent Advances. IntechOpen. https://doi.org/10.5772/intechopen.106184
ISBN978-1-80356-087-8
URIhttp://hdl.handle.net/10576/37762
AbstractAutoimmune diseases have emerged as a pandemic in our modern societies, especially after World War II. There are currently more than 80 autoimmune diseases that compromise the lives of millions of patients around the world. There is a variety of factors that are involved in the pathogenesis of autoimmune diseases that vary from environmental factors to genetic susceptibility. The GI tract is one of the most susceptible sub-systems in human bodies for autoimmune organ-specific diseases. There are five autoimmune GI tract diseases that are most common. This review consists of two chapters. In part I, we shed the light on introducing the concept of autoimmunity, the description of the disease’s pathogenesis and the diagnosis, the link between the gut and brain through what is known as the gut-brain axis, and the relationship of this axis in GI autoimmune diseases. In part II, we will shed light on the role of antibodies as markers for the prediction of the disease, artificial intelligence in GI autoimmune diseases, the nutritional role and implications in the five GI autoimmune diseases, and finally the treatment of those diseases.
SponsorThis section of your manuscript may also include funding information. The publication of this chapter is funded by Qatar National Library.
Languageen
PublisherIntechOpen
Subjectachalasia
atrophic autoimmune gastritis
celiac disease
eosinophilic esophagitis
inflammatory bowel diseases
Crohn disease
ulcerative colitis
immunological continuum
epithelial barrier dysfunction
gut-brain axis
TitleAutoimmune Diseases of the GI Tract Part I: Etiology and Pathophysiology
TypeBook chapter
dc.accessType Open Access


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