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AuthorButnariu, Monica
AuthorQuispe, Cristina
AuthorHerrera-Bravo, Jesús
AuthorPentea, Marius
AuthorSarac, Ioan
AuthorKüşümler, Aylin Seylam
AuthorÖzçelik, Beraat
AuthorPainuli, Sakshi
AuthorSemwal, Prabhakar
AuthorImran, Muhammad
AuthorGondal, Tanweer Aslam
AuthorEmamzadeh-Yazdi, Simin
AuthorLapava, Natallia
AuthorYousaf, Zubaida
AuthorKumar, Manoj
AuthorEid, Ali Hussein
AuthorAl-Dhaheri, Yusra
AuthorSuleria, Hafiz Ansar Rasul
AuthorContreras, María del Mar
AuthorSharifi-Rad, Javad
AuthorCho, William C.
Available date2023-03-05T08:34:41Z
Publication Date2022-01-01
Publication NameOxidative Medicine and Cellular Longevity
Identifierhttp://dx.doi.org/10.1155/2022/2041769
CitationMonica Butnariu, Cristina Quispe, Jesús Herrera-Bravo, Marius Pentea, Ioan Sarac, Aylin Seylam Küşümler, Beraat Özçelik, Sakshi Painuli, Prabhakar Semwal, Muhammad Imran, Tanweer Aslam Gondal, Simin Emamzadeh-Yazdi, Natallia Lapava, Zubaida Yousaf, Manoj Kumar, Ali Hussein Eid, Yusra Al-Dhaheri, Hafiz Ansar Rasul Suleria, María del Mar Contreras, Javad Sharifi-Rad, William C. Cho, "Papaver Plants: Current Insights on Phytochemical and Nutritional Composition Along with Biotechnological Applications", Oxidative Medicine and Cellular Longevity, vol. 2022, Article ID 2041769, 23 pages, 2022. https://doi.org/10.1155/2022/2041769
ISSN19420900
URIhttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85134270312&origin=inward
URIhttp://hdl.handle.net/10576/40648
AbstractThe genus Papaver is highly esteemed in the pharmacy industry, in the culinary field, and as ornamental plants. These plants are also valued in traditional medicine. Among all Papaver species, Papaver somniferum L. (opium poppy) is the most important species in supplying phytochemicals for the formulation of drugs, mainly alkaloids like morphine, codeine, rhoeadine, thebaine, and papaverine. In addition, Papaver plants present other types of phytochemicals, which altogether are responsible for its biological activities. Therefore, this review covers the phytochemical composition of Papaver plants, including alkaloids, phenolic compounds, and essential oils. The traditional uses are reviewed along with their pharmacological activities. Moreover, safety aspects are reported to provide a deep overview of the pharmacology potential of this genus. An updated search was carried out in databases such as Google Scholar, ScienceDirect, and PubMed to retrieve the information. Overall, this genus is a rich source of alkaloids of different types and also contains interesting phenolic compounds, such as anthocyanins, flavonols, and the characteristic indole derivatives nudicaulins. Among other pharmacological properties, numerous preclinical studies have been published about the analgesic, anticancer, antimicrobial, antioxidant, and antidiabetic activities of Papaver plants. Although it highlights the significant impact of this genus for the treatment of a variety of diseases and conditions, as a future prospect, characterization works accompanying preclinical studies are required along with clinical and toxicology studies to establish a correlation between the scientific and traditional knowledge.
Languageen
PublisherHindawi
SubjectPlant Complexes
Papaver
Papaver somniferum L.
opium poppy
TitlePapaver Plants: Current Insights on Phytochemical and Nutritional Composition Along with Biotechnological Applications
TypeArticle
Volume Number2022
ESSN1942-0994
dc.accessType Open Access


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