Show simple item record

AuthorKhaled, Sadek
AuthorAbdelhafez, Ibrahim
AuthorAl-Hashimi, Israa
AuthorAl-Shafi, Wadha
AuthorTarmizi, Fatihah
AuthorAl-Marri, Hissa
AuthorAlzohari, Nada
AuthorBalideh, Mohammad
AuthorCarr, Alison
Available date2023-03-20T07:32:51Z
Publication Date2021-10-27
Publication NamePrimary Care Diabetes
Identifierhttp://dx.doi.org/10.1016/j.pcd.2021.10.002
CitationSadek, K., Abdelhafez, I., Al-Hashimi, I., Al-Shafi, W., Tarmizi, F., Al-Marri, H., ... & Carr, A. (2022). Screening for diabetes and impaired glucose metabolism in Qatar: Models’ development and validation. Primary Care Diabetes, 16(1), 69-77.
ISSN1751-9918
URIhttps://www.sciencedirect.com/science/article/pii/S1751991821001868
URIhttp://hdl.handle.net/10576/41200
AbstractAimTo establish two scoring models for identifying individuals at risk of developing Impaired Glucose Metabolism (IGM) or Type two Diabetes Mellitus (T2DM) in Qatari. Materials and methodsA sample of 2000 individuals, from Qatar BioBank, was evaluated to determine features predictive of T2DM and IGM. Another sample of 1000 participants was obtained for external validation of the models. Several scoring models screening for T2DM were evaluated and compared to the model proposed by this study. ResultsAge, gender, waist-to-hip-ratio, history of hypertension and hyperlipidemia, and levels of educational were statistically associated with the risk of T2DM and constituted the Qatar diabetes mellitus risk score (QDMRISK). Along with, the 6 aforementioned variables, the IGM model showed that BMI was statistically significant. The QDMRISK performed well with area under the curve (AUC) 0.870 and .815 in the development and external validation cohorts, respectively. The QDMRISK showed overall better accuracy and calibration compared to other evaluated scores. The IGM model showed good accuracy and calibration, with AUCs .796 and .774 in the development and external validation cohorts, respectively. ConclusionsThis study developed Qatari-specific diabetes and IGM risk scores to identify high risk individuals and can guide the development of a nationwide primary prevention program.
Languageen
PublisherElsevier
SubjectDiabetes
Impaired glucose metabolism
Risk score
Epidemiology
Public health
TitleScreening for diabetes and impaired glucose metabolism in Qatar: Models’ development and validation
TypeArticle
Pagination69-77
Issue Number1
Volume Number16
dc.accessType Abstract Only


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record