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Automated quantification of penile curvature using artificial intelligence
( Frontiers Media S.A. , 2022 , Article)Objective: To develop and validate an artificial intelligence (AI)-based algorithm for capturing automated measurements of Penile curvature (PC) based on 2-dimensional images. Materials and methods: Nine 3D-printed ... -
Cardioprotective Effect of Rheum turkestanicum Against Doxorubicin-Induced Toxicity in Rats
( Frontiers Media S.A. , 2022 , Article)Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum ... -
Carnosol Is a Novel Inhibitor of p300 Acetyltransferase in Breast Cancer
( Frontiers Media S.A. , 2021 , Article)Carnosol, a natural polyphenol abundant in edible plants such as sage, rosemary, and oregano, has shown promising anticancer activity against various types of cancers. Nonetheless, very little is known about its molecular ... -
Cellular and molecular targets of menthol actions
( Frontiers Media S.A. , 2017 , Article Review)Menthol belongs to monoterpene class of a structurally diverse group of phytochemicals found in plant-derived essential oils. Menthol is widely used in pharmaceuticals, confectionary, oral hygiene products, pesticides, ... -
Corrigendum: What Is the Modern Human Eating? Dietary Transition of the Age-Old to the Modern Man of India(Public Health Rev., (2022), 43, (1604058), 10.3389/phrs.2022.1604058)
( Frontiers Media S.A. , 2024 , Article)In the published article, there was an error in Affiliation of Giridhara R. Babu. Instead of “Indian Institute of Public Health, Bengaluru, India”, it should be “Department of Population Medicine, College of Medicine, QU ... -
Covid-19 in pediatric patients: A focus on CHD patients
( Frontiers Media S.A. , 2020 , Article)Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease ... -
Current status of tissue engineering in the management of severe hypospadias
( Frontiers Media S.A. , 2018 , Article Review)Hypospadias, characterized by misplacement of the urinary meatus in the lower side of the penis, is a frequent birth defect in male children. Because of the huge variation in the anatomic presentation of hypospadias, no ... -
Disease-Associated Regulation of Non-Coding RNAs by Resveratrol: Molecular Insights and Therapeutic Applications
( Frontiers Media S.A. , 2022 , Article Review)There have been significant advances, particularly over the last 20 years, in the identification of non-coding RNAs (ncRNAs) and their pathophysiological role in a wide range of disease states, particularly cancer and other ... -
Editorial: Methods and application in cardiovascular and smooth muscle pharmacology: 2021
( Frontiers Media S.A. , 2022 , Other)Despite significant advances in basic, translational, and clinical research tackling heart disease, cardiovascular pathologies remain among the leading causes of mortality and morbidity worldwide, being responsible for ... -
Editorial: Role of Iron in Bacterial Pathogenesis
( Frontiers Media S.A. , 2018 , Article)Iron is the fourth-most abundant element on the earth, and it is needed by most organisms, including bacteria. It exists in two oxidation states, Fe2+ and Fe3+, and is involved in many oxido-reduction reactions (Andrews ... -
Editorial: The effect of COVID-19 on hematological disease diagnosis, management and outcomes
( Frontiers Media S.A. , 2023 , Other)Lee, Chieng, Lau et al. studied the effects of coronavirus disease-2019 (COVID-19) on the clinical presentation, radiological findings, and outcomes of the infection in patients with hemoglobinopathies. They found that the ... -
Essential Role of Complement in Pregnancy: From Implantation to Parturition and Beyond
( Frontiers Media S.A. , 2020 , Article)The complement cascade was identified over 100 years ago, yet investigation of its role in pregnancy remains an area of intense research. Complement inhibitors at the maternal-fetal interface prevent inappropriate complement ... -
Haematococcus pluvialis Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells
( Frontiers Media S.A. , 2022 , Article)Breast cancer (BC) is the most common malignant cancer in females worldwide. Drug resistance, toxicity, and the failure of current therapies to completely cure BC has challenged conventional medicine. Consequently, ... -
Hydroxychloroquine in COVID-19 Patients: Pros and Cons
( Frontiers Media S.A. , 2020 , Article)The pandemic of COVID-19, caused by SARS-CoV-2, has recently overwhelmed medical centers and paralyzed economies. The unparalleled public distress caused by this pandemic mandated an urgent quest for an effective approach ... -
Morphometric Analysis of the Corpus Callosum According to Age and Sex in Middle Eastern Arabs: Racial Comparisons and Clinical Correlations to Autism Spectrum Disorder
( Frontiers Media S.A. , 2020 , Article)This study sought to examine the influence of age and sex on morphometric measurements of the corpus callosum (CC) within Middle Eastern Arab population, in order to obtain reference data and conduct racial comparisons ... -
Perirenal Adipose Tissue Inflammation: Novel Insights Linking Metabolic Dysfunction to Renal Diseases
( Frontiers Media S.A. , 2021 , Article)A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it contributes to energy homeostasis and provides insulation for internal organs. Adipocytes were previously thought to be a passive ... -
Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis
( Frontiers Media S.A. , 2023 , Article)Background and objectives: Polypharmacy and chronic kidney disease (CKD) are becoming increasingly common due to an ageing population and the rise of multimorbidity. In line with the therapeutic guidelines, managing CKD ... -
Prevalence of Venous Thromboembolism in Critically Ill COVID-19 Patients: Systematic Review and Meta-Analysis
( Frontiers Media S.A. , 2021 , Article)Background: Recent studies revealed a high prevalence of venous thromboembolism (VTE) events in coronavirus disease 2019 (COVID-19) patients, especially in those who are critically ill. Available studies report varying ... -
Qatar Healthcare Workers' COVID-19 Vaccine Hesitancy and Attitudes: A National Cross-Sectional Survey
( Frontiers Media S.A. , 2021 , Article)Introduction: Healthcare workers are the critical frontline workforce of the COVD-19 pandemic and are considered a target group for vaccination. Hesitancy to vaccinate is a major concern that can jeopardize the vaccination ... -
Respiratory virus type to guide predictive enrichment approaches in the management of the first episode of bronchiolitis: A systematic review
( Frontiers Media S.A. , 2022 , Other)It has become clear that severe bronchiolitis is a heterogeneous disease; even so, current bronchiolitis management guidelines rely on the one-size-fits-all approach regarding achieving both short-term and chronic outcomes. ...