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Now showing items 181-190 of 1068
A large, highly vascularized sacrococcygeal teratoma in a preterm male infant: A case report.
(
Elsevier
, 2021 , Article)
Sacrococcygeal teratoma (SCT) is a rare tumor with an incidence of 1:35.000/40.000 live births. SCTs are composed of both cystic and solid components. Predominantly cystic SCTs are more likely to be benign and have a better ...
Circulating miRNAs in HER2-Positive and Triple Negative Breast Cancers: Potential Biomarkers and Therapeutic Targets.
(
MDPI
, 2020 , Article)
Breast cancer is one of the most prevalent diseases among women worldwide and is highly associated with cancer-related mortality. Of the four major molecular subtypes, HER2-positive and triple-negative breast cancer (TNBC) ...
Prenatal and early life origins of adolescence sleep problems: evidence from a birth cohort.
(
De Gruyter
, 2018 , Article)
Purpose This study aims to identify the prenatal and early life predictors of adolescence sleep problems. Methods Sleep data (n = 5081) from the 14-year (13.92 ± 0.34 years) follow-up of a birth cohort were analyzed to ...
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
(
Taylor & Francis
, 2019 , Article)
Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize that the ...
Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targets
(
American Society for Clinical Investigation
, 2019 , Article)
Tumor-infiltrating lymphocytes (TILs) are widely associated with positive outcomes, yet carry key indicators of a systemic failed immune response against unresolved cancer. Cancer immunotherapies can reverse their tolerance ...
Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivity
(
American Society for Clinical Investigation
, 2019 , Article)
Itch induces scratching that removes irritants from the skin, whereas pain initiates withdrawal or avoidance of tissue damage. While pain arises from both the skin and viscera, we investigated whether pruritogenic irritant ...
Water-pipe smoking promotes epithelial-mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways.
(
BioMed Central Ltd.
, 2018 , Article)
With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women's health. The main goal of this study is to identify the potential outcome of WPS on human breast cancer ...
Composition of the immune microenvironment differs between carcinomas metastatic to the lungs and primary lung carcinomas.
(
Elsevier
, 2018 , Article)
Lungs are among the most common sites for development of both primary and metastatic carcinomas. Tumor cells expression (TC) of PD-L1 is an important predictor of the of response to immune check-point inhibition in NSCLC, ...
The role of the Hedgehog signaling pathway in cancer: A comprehensive review.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2018 , Article)
The Hedgehog (Hh) signaling pathway was first identified in the common fruit fly. It is a highly conserved evolutionary pathway of signal transmission from the cell membrane to the nucleus. The Hh signaling pathway plays ...
Towards Molecular Profiling in Multiple Myeloma: A Literature Review and Early Indications of Its Efficacy for Informing Treatment Strategies.
(
MDPI
, 2018 , Article)
Multiple myeloma (MM), the second most common hematologic malignancy, is characterized by the clonal expansion of plasma cells. Despite dramatic improvements in patients' survival over the past decade due to advances in ...