Search
Now showing items 11-20 of 20
Neisseria gonorrhoeae Ketol-Acid Reductoisomerase Is a Potential Therapeutic Target
(
IntechOpen
, 2022 , Book chapter)
The host-adapted human pathogen Neisseria gonorrhoeae is the causative agent of sexually transmitted infection gonorrhea. The increased emergence of gonorrhea infections worldwide, associated with the surging resistance ...
E-cadherin/catenin complex modulations in human oral cancer
(
Springer Netherlands
, 2015 , Book chapter)
Oral cancer is a common neoplasm in both male and female worldwide; the incidence and mortality of this cancer have increased over the past decades. Cancer metastasis is a major cause of morbidity and mortality in oral ...
Detection of β-Arrestin-Mediated G Protein-Coupled Receptor Ubiquitination Using BRET.
(
Humana Press, New York, NY
, 2019 , Book chapter)
Ubiquitination of G protein-coupled receptors (GPCRs) is an important dynamic posttranslational modification that has been linked to the intracellular trafficking of internalized GPCRs to lysosomes. Ubiquitination of GPCRs ...
Oral Vaccine Delivery: The Coming Age of Particulate Vaccines to Elicit Mucosal Immunity
(
Springer
, 2020 , Book chapter)
With the evolution of different challenging diseases, there is an urgent need of vaccine development against them to save millions of lives around the world. Particlulate delivery system plays an important role by acting ...
DNA Damage/Repair Management in Cancers
(
Routledge
, 2021 , Book chapter)
DNA damage can alter nucleotide sequences and lead to expression of dysfunctional proteins that impact normal cellular physiology. Sources of DNA damage can be endogenous or exogenous and include reactive oxygen species ...
RKIP in human diseases and its potential as a prognostic indicator and therapeutic target
(
Elsevier
, 2020 , Book chapter)
The Raf kinase inhibitory protein (RKIP) is an inhibitor of the RAF/MEK/ERK and NF-κB signaling pathways, through which it regulates several key processes of the cell's physiology, such as its proliferation, motility and ...
Autism and the Scaffolding Protein Neurobeachin
(
Springer
, 2022 , Book chapter)
Autism is a group of early onsets, diverse, lifelong, neurodevelopmental conditions that affect social interaction, verbal and non-verbal communications as well as behavior. It is a multifactorial condition, which results ...
Retinoids and Reactive Oxygen Species in Cancer Cell Death and Therapeutics
(
Springer Nature
, 2022 , Book chapter)
Retinoids are a large family of structurally related natural and synthetic molecules that exhibit a variety of effects in embryogenesis and adult life. The parent compound of retinoids is vitamin A which was first discovered ...
Psychosocial treatments for substance use disorders
(
Nova Science Publishers, Inc.
, 2022 , Book chapter)
Worldwide use of illicit drugs is increasing, and substance use disorders (SUDs) have become a significant mental health problem in the West. Although the majority of young people do not use illicit drugs and of those who ...
Pediatric sleep disorders
(
Nova Science Publishers, Inc.
, 2022 , Book chapter)
Patterns of normal sleep are considered, including the circadian cycle, which is considered the body's internal clock, REM, and NREM sleep. Sleep disorders are a prevalent problem in the pediatric population, affecting ...