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Laplace approximation, penalized quasi-likelihood, and adaptive Gauss-Hermite quadrature for generalized linear mixed models: Towards meta-analysis of binary outcome with sparse data
(
BMC
, 2020 , Article)
© 2020 The Author(s). Background: In meta-analyses of a binary outcome, double zero events in some studies cause a critical methodology problem. The generalized linear mixed model (GLMM) has been proposed as a valid ...
Arcsine-based transformations for meta-analysis of proportions: Pros, cons, and alternatives
(
Wiley Open Access
, 2020 , Article)
© 2020 The Authors. Health Science Reports published by Wiley Periodicals LLC. Meta-analyses have been increasingly used to synthesize proportions (eg, disease prevalence) from multiple studies in recent years. Arcsine-based ...
Comparative Genomic and Transcriptomic Analyses of Mycobacterium kansasii Subtypes Provide New Insights Into Their Pathogenicity and Taxonomy
(
Frontiers Media
, 2020 , Article)
Mycobacterium kansasii is an important opportunistic pathogen of humans and has a
close phylogenetic relationship with Mycobacterium tuberculosis. Seven subtypes (I–VII)
have been identified using molecular biology ...
Dishevelled family proteins (DVL1-3) expression in intrauterine growth restriction (IUGR) placentas.
(
BJBMS
, 2020 , Article)
Dishevelled family proteins (DVL1, DVL2, and DVL3) are cytoplasmic proteins that are involved in canonical and non-canonical Wnt signaling pathway during embryonic development. The role of DVL proteins in the placental ...
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.
(
BMC
, 2020 , Article)
Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson's disease (PD), multiple system atrophy, and dementia ...
Protocols for meta-analysis of intervention safety seldom specified methods to deal with rare events
(
Elsevier
, 2020 , Article Review)
ObjectivesMeta-analyses of rare events often generate unstable results, and selective reporting of the results may mislead the health care decision. Developing a synthesis plan for rare events in protocol may help to ...
Molecular profiling of the metaplastic spindle cell carcinoma of the breast reveals potentially targetable biomarkers
(
Elsevier
, 2020 , Article)
IntroductionSpindle cell carcinoma is a rare subtype of metaplastic breast cancer (MBC), with triple-negative (TNBC: ER-/PR-/Her2-) phenotype. It is associated with a marked resistance to conventional chemotherapy and has ...
Women's Health and Well-Being in the United Nations Sustainable Development Goals: A Narrative Review of Achievements and Gaps in the Gulf States.
(
MDPI
, 2020 , Article)
In 2014, United Nations member states proposed a set of sustainable development goals (SDGs) to help further the millennium development goals that they had proposed in New York in 2000. Of these 13 SDGs, Goal 3 (i.e., SDG ...
Crosstalk between HER2 and PD-1/PD-L1 in Breast Cancer: From Clinical Applications to Mathematical Models.
(
Springer
, 2020 , Article)
Breast cancer is one of the major causes of mortality in women worldwide. The most aggressive breast cancer subtypes are human epidermal growth factor receptor-positive (HER2) and triple-negative breast cancers. Therapies ...
Bowel Dilatation on Initial Plane Abdominal Radiography May Help to Assess the Severity of Necrotizing Enterocolitis in Preterm Infants.
(
MDPI
, 2020 , Article)
Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal emergency associated with prematurity. Timely diagnosis and adequate treatment are crucial to reduce the morbidity and mortality of the ...