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Now showing items 51-60 of 110
COVID-19: potential therapeutics for pediatric patients
(
Springer
, 2021 , Article Review)
The global spread of COVID-19 has imparted significant economic, medical, and social burdens. Like adults, children are affected by this pandemic. However, milder clinical symptoms are often experienced by them. Only a ...
Deregulation of cell growth and apoptosis in UV-induced melanomagenesis
(
Frontiers in Bioscience
, 2020 , Article Review)
We have previously characterized the role of p16/Rb in coordinating the early events in UVB-irradiated skin. As an extension to this work, normal melanocytes and mutant p16-inducible melanoma cell models were employed to ...
Unveiling a Biomarker Signature of Meningioma: The Need for a Panel of Genomic, Epigenetic, Proteomic, and RNA Biomarkers to Advance Diagnosis and Prognosis
(
MDPI
, 2023 , Article Review)
Meningiomas are the most prevalent primary intracranial tumors. The majority are benign but can undergo dedifferentiation into advanced grades classified by World Health Organization (WHO) into Grades 1 to 3. Meningiomas’ ...
Anticancer Potential of the Cyclolinopeptides
(
MDPI
, 2023 , Article Review)
Novel therapeutic agents to combat cancer is an active area of research, as current treatment options have limitations in efficacy and tolerability. One of these therapeutic agents in our immediate environment is ...
Emerging roles of activating transcription factor 2 in the development of breast cancer: a comprehensive review.
(
Oxford University Press
, 2023 , Article Review)
Activating transcription factor 2 (ATF2) is a member of the leucine zipper family of DNA binding proteins that are responsible for regulating various genes that play an essential role in major biological and cellular ...
Ultrasound-Based Image Analysis for Predicting Carotid Artery Stenosis Risk: A Comprehensive Review of the Problem, Techniques, Datasets, and Future Directions
(
MDPI
, 2023 , Article Review)
The carotid artery is a major blood vessel that supplies blood to the brain. Plaque buildup in the arteries can lead to cardiovascular diseases such as atherosclerosis, stroke, ruptured arteries, and even death. Both ...
Advances in nanotechnology-enabled drug delivery for combining PARP inhibitors and immunotherapy in advanced ovarian cancer.
(
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
, 2023 , Article Review)
Advanced ovarian cancer is a malignancy that spreads beyond the ovaries to the pelvis, abdomen, lungs, or lymph nodes. Effective treatment options are available to improve survival rates in patients with advanced ovarian ...
Testosterone and Covid-19: An update
(
John Wiley and Sons Ltd
, 2023 , Article Review)
There is overwhelming evidence to suggest that male gender is at a higher risk of developing more severe Covid-19 disease and thus having poorer clinical outcomes. However, the relationship between testosterone (T) and ...
Infection with Helicobacter pylori may predispose to atherosclerosis: role of inflammation and thickening of intima-media of carotid arteries
(
Frontiers Media
, 2023 , Article Review)
Atherosclerosis is a major instigator of cardiovascular disease (CVD) and a main cause of global morbidity and mortality. The high prevalence of CVD calls for urgent attention to possible preventive measures in order to ...
Genomic Newborn Screening for Pediatric Cancer Predisposition Syndromes: A Holistic Approach
(
MDPI
, 2024 , Article Review)
As next-generation sequencing (NGS) has become more widely used, germline and rare genetic variations responsible for inherited illnesses, including cancer predisposition syndromes (CPSs) that account for up to 10% of ...